Results 71 to 80 of about 3,674 (185)

Modified colorimetric ultramicro method for estimating Nefa in serum [PDF]

Journal of Clinical Pathology, 1968
A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 μl samples; it is thus suitable for
openaire   +2 more sources

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, Volume 270, Issue 1, Page 98-113, September 2026.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

Effects of Nano Zinc Oxide Supplementation on Oxidative Stress and Selected Metabolic Parameters During the Transition Period in Lacaune Ewes

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano zinc oxide supplementation did not significantly affect TOS, TAS or OSI in transition period Lacaune ewes. However, treatment related responses were observed for BHBA, phosphorus and total cholesterol, suggesting limited metabolic effects that require cautious interpretation.
Gaye Bulut, Neşe Hayat Aksoy, Caner Ozturk   +2 more
wiley   +1 more source

Visceral fat lipolysis by pancreatic lipases worsens heart failure

Cell Reports Medicine
Summary: Heart failure can be worse when associated with obesity, elevated serum pancreatic enzymes, elevated non-esterified fatty acids (NEFAs), or acute pancreatitis (AP).
Nabil Smichi, Biswajit Khatua, Sergiy Kostenko, Cristiane de Oliveira, Bara El Kurdi, Kalpit Himmatbhai Devani, Shubham Trivedi, Megan Summers, Bryce McFayden, Sarah Navina, Krutika Patel, Sarah Jahangir, Marek Belohlavek, Vijay P. Singh   +13 more
doaj   +1 more source

Pre‐Exercise Galactose or Lactose Reduces Glycaemic Excursions During Exercise in Adults With Type 1 Diabetes: A Randomised, Double‐Blind, Crossover Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7825-7833, September 2026.
ABSTRACT Aims To test whether pre‐exercise galactose and lactose reduce glycaemic excursions during exercise compared with dextrose while maintaining protection against hypoglycaemia compared with placebo in adults with Type 1 diabetes Methods In a randomised, double‐blind, 4‐condition crossover trial, 14 adults with Type 1 diabetes completed four 60 ...
Karoline R. Schmidt, Rakel F. Johansen, Simon B. Riis, Mads S. Larsen, Henrik Støvring, Gareth A. Wallis, David Rowlands, Lars C. Gormsen, Esben Søndergaard   +8 more
wiley   +1 more source

Subgroups of Adult‐Onset Diabetes: A Prospective Follow‐Up Study of Progression of Insulin Resistance and Deficiency and Association With Liver Steatosis and Fibrosis

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8004-8015, September 2026.
ABSTRACT Aims To assess progression of insulin deficiency and resistance in diabetes, the stability of cluster‐based subgrouping, and the association between steatotic liver disease (SLD), liver fibrosis (LF), and tissue insulin resistance. Materials and Methods Participants from a regional diabetes register were studied within 3 years from diagnosis ...
Aleksi Laitinen, Annemari Käräjämäki, Aki J. Käräjämäki, Samu Kurki, Liisa Hakaste, Olof Asplund, Johan Hultman, Kaj Lahti, Mikko Lehtovirta, Emma Ahlqvist, Tiinamaija Tuomi   +10 more
wiley   +1 more source

Effect of Guanylic Acid on Plasma NEFA Response to Stress.

Experimental Biology and Medicine, 1960
SummaryPretreatment with hydrocortisone restores plasma NEFA response of adrenalectomized animals to normal but is without effect on intact rats. Pretreatment with guanylic acid, a purine nucleotide, abolishes NEFA response to fasting and tourniquet stress in the normal animal.
J, KABAL, E R, RAMEY
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Aerobic Exercise Training Increases Circulating sRAGE in Adults With Type 2 Diabetes: Associations With Sheddase Regulation

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8157-8171, September 2026.
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins, Corey E. Mazo, James Shadiow, Pallavi Varshney, Edwin R. Miranda, Victoria R. Miranda, Maggie Eisenberg, Jane E. Nakamura, Elif A. Oral, Jacob M. Haus   +9 more
wiley   +1 more source

Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Hiroyuki Mori, Hadla Hariri, William Moe, Sophia Durham, Yuridia Guzman, Emma Paulsson, Rachel C. Simmermon, Parth B. Bhanderi, Sydney K. Peterson, Mia J. Dickson, Charles R. Evans, Ormond A. MacDougald   +11 more
wiley   +1 more source

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha, Eloisa Vilas‐Boas, Camille C. Caldeira da Silva, Everton L. Vogt, Marcos Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara I. C. Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia J. Kowaltowski   +9 more
wiley   +1 more source