Results 51 to 60 of about 4,359 (219)

Early diabetes‐like phenotypes in germ‐free mice induced by gut microbiota from patients with type 2 diabetes

Animal Models and Experimental Medicine, EarlyView.
Gut microbiota from patients with type 2 diabetes induced early diabetes‐like phenotypes in germ‐free mice, including progressive glucose intolerance and mild renal injury. Longitudinal profiling revealed persistent dysbiosis preceding stable metabolic dysfunction, with coordinated fecal and plasma metabolite alterations and a prominent L‐Dopa ...
Jianghao Feng, Xing Liu, Hua Zhu, Yun Yang, Wei Liu, Xiaoliang Jiang, Zhiwei Yang   +6 more
wiley   +1 more source

Influence of endogenous NEFA on beta cell function in humans [PDF]

Diabetologia, 2015
It is a commonly held view that chronically elevated NEFA levels adversely affect insulin secretion and insulin action (lipotoxicity). However, the effect of NEFA on beta cell function has only been explored using acute NEFA elevations. Our aim was to analyse the relationship between endogenous NEFA levels and beta cell function.In 1,267 individuals ...
Rebelos, Eleni, Seghieri, Marta, NATALI, ANDREA, Balkau, Beverly, Golay, Alain, Piatti, Pier Marco, Lalic, Nebojsa M., Laakso, Markku, Mari, Andrea, Ferrannini, Ele   +9 more
openaire   +5 more sources

Trend analysis of temperature and rainfall in south gonder zone, anhara ethiopia.

Journal of Degraded and Mining Lands Management, 2018
This study mainly focuses on exploring trend analysis of temperature and rainfall in the case of south Gonder zone. The analysis is based on the temperature and rainfall variation in south Gonder zone over three stations at Addis Zemen, Nefas Mewcha and ...
Birhan Getachew
doaj   +1 more source

Indole‐3‐Acetic Acid Protects Bovine Hepatocytes Against Palmitic Acid‐Induced Lipid Accumulation and ER Stress Through SIRT3

Animal Research and One Health, EarlyView.
Cows with ketosis during the perinatal period often experience damage to the liver, a core metabolic organ, thereby exacerbating the disease's inherent vicious cycle. This study indicates that serum 3‐IAA concentrations were reduced in ketotic cows and show a significant negative correlation with hepatic TG content.
Dandan Qi, Chenchen Zhao, Guiying Li, Jinxia Li, Menglin Liu, Fanrong Kong, Enzhu Li, Jie Gao, Wenqi Liao, Akos Kenez, Wenwen Gao, Yuxiang Song, Xiliang Du, Guowen Liu, Xinwei Li, Lin Lei   +15 more
wiley   +1 more source

An overview on how cumulus cells interact with the oocyte in a condition with elevated NEFA levels in dairy cows [PDF]

, 2019
Metabolic stress in humans and animals is associated with impaired fertility. A major characteristic of metabolic stress is elevated levels of free fatty acids (NEFAs) in blood due to mobilization of body fat reserves.
Sub Celbiologisch lab., LS GZ Landbouwhuisdieren, dES/dFAH FR, Aardema, Hilde, van Tol, Helena T.A., Vos, Peter L.A.M., dFAH AVR, LS Klinische Reproductie   +7 more
core   +1 more source

Short‐term clinical responses in horses and ponies treated with canagliflozin: A clinical field study

Equine Veterinary Journal, EarlyView.
Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom, Sanna Truelsen Lindåse, Monika Wartel, Johan Bröjer   +3 more
wiley   +1 more source

Hector’s image as the first nefas in Senecan Troades [PDF]

, 2012
En la presente comunicación nos centraremos en el análisis de la imagen de Héctor en Troyanas de Séneca. Hemos observado que con ella los personajes definen y describen situaciones.
Pedernera, Elizabet Soledad
core  

Plasma Metabolomic Analysis Reveals the Relationship between Immune Function and Metabolic Changes in Holstein Peripartum Dairy Cows

Metabolites, 2022
Dairy cows undergo dynamic physiological changes from late gestation to early lactation, including metabolic changes and immune dysfunction. The aim of this study was to investigate the relationship between immune function and metabolic changes in ...
Zhuo Yang, Fang Luo, Guolin Liu, Zhengzhong Luo, Sijia Ma, Hang Gao, Hailong He, Jinzhong Tao   +7 more
doaj   +1 more source

Impact of Heated Versus Unheated Cooking Oil on Postprandial Vascular Function and Metabolism

Lipids, EarlyView.
ABSTRACT The impact of repeated heating of seed‐based culinary oils on cardiometabolic health has not been well established. Heating oils to high temperatures (> 150°C) causes lipid peroxidation, thus generating potentially harmful compounds that may impair vascular function. This randomized, single‐blind, crossover study investigated the acute effects
Rosiered Brownson‐Smith, Jo Bruce, Esmat Abbas, Sarah Fissler, Wendy Hall, Sarah Berry   +5 more
wiley   +1 more source

Iam scelus esse contextum (Questions naturelles IVa, praef. 19). La tragédie sénéquienne comme eidos du nefas

, 2015
La conscience théorique de Sénèque le philosophe au sujet de l’eidos tragique apparaît suffisamment claire au cours de sa prose. Grâce justement à son haut statut formel, la tragédie est en mesure de représenter la inmanis et inuisa materia du mal, nœud ...
Mazzoli, Giancarlo
core   +1 more source