Results 91 to 100 of about 4,852 (215)

Loss of Abhd2 does not alter the physiological response to prolonged fasting or refeeding.

open access: yes, 2023
Following a 24-hr fast, female mice averaged a 1.7 ± 0.9 gm weight loss and an average 1.1 ± 0.1 gm weight gain following the 6-hour refeed period and were not different for Abhd2KO versus WT mice (A).
Alan D. Attie (42426)   +9 more
core   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Hepatic Overexpression of Lysophospholipid Acyltransferase LPLAT14/MBOAT1 Ameliorates Mild Liver Injury During Early High‐Fat Diet Feeding

open access: yesFASEB BioAdvances, Volume 8, Issue 11, November 2026.
Using an improved adenovirus vector, we investigated the effects of hepatic LPLAT14 overexpression on high‐fat diet (HFD)‐induced metabolic disorders and mild liver injury in mice. LPLAT14 selectively increased oleic acid (OA)‐containing phosphatidylserine (PS) species in the liver. This specific lipidomic remodeling attenuated mild liver injury during
Sho Hori   +7 more
wiley   +1 more source

Iam scelus esse contextum (Questions naturelles IVa, praef. 19). La tragédie sénéquienne comme eidos du nefas

open access: yes, 2015
La conscience théorique de Sénèque le philosophe au sujet de l’eidos tragique apparaît suffisamment claire au cours de sa prose. Grâce justement à son haut statut formel, la tragédie est en mesure de représenter la inmanis et inuisa materia du mal, nœud ...
Mazzoli, Giancarlo
core   +1 more source

Nefas. Empietà, reticenza e dinamiche della comunicazione nelle tragedie di Seneca

open access: yes, 2019
The word nefas, a key concept of Seneca's tragic idea, means an act being at the same time impious and unspeakable. The paper aims to understand whether and how the notion of unspeakability - related in particular to unnatural acts such as incest and ...
Bonandini, Alice
core   +1 more source

Milk components as potential indicators of energy status in early lactation Holstein dairy cows from two farms

open access: yesAnimal
Negative energy balance (NEB) is a serious problem in most dairy cows. It occurs most frequently after calving, when cows are unable to consume sufficient DM to meet their energy requirements during early lactation.
M. Štolcová, L. Bartoň, D. Řehák
doaj   +1 more source

Platelet Serotonin Levels Are Associated with Plasma Soluble Leptin Receptor Concentrations in Normoglycemic Women

open access: yesJournal of Diabetes Research, 2019
Most peripheral serotonin (5-hydroxytryptamine (5HT)) is synthetized in the gut with platelets being its main circulating reservoir. 5HT is acting as a hormone in key organs to regulate glucose and lipid metabolism. However, the relation between platelet
Luis Rodrigo Cataldo   +7 more
doaj   +1 more source

Endurance Training Improves Insulin Sensitivity, Metabolic Flexibility, and Mitochondrial Function in Type 2 Diabetes

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 11, November 2026.
ABSTRACT To determine how endurance training influences insulin sensitivity, metabolic flexibility, and mitochondrial function in individuals with and without type 2 diabetes (T2D). Insulin sensitivity (2‐step hyperinsulinaemic–isoglycaemic clamp), metabolic flexibility, and mitochondrial respiratory capacity and H2O2 emission were assessed in ...
Maria Hansen   +14 more
wiley   +1 more source

Acute sprint exercise transcriptome in adipose tissue of healthy adults: Associations with growth hormone

open access: yesPhysiological Reports, Volume 14, Issue 21, November 2026.
Abstract We hypothesised that acute sprint exercise induces changes in adipose tissue (AT) gene expression related to lipolysis, and that growth hormone (GH) contributes to this. Healthy males and females were randomised to perform 3 × 30‐s all‐out cycle sprints (SIT, N = 12) or unloaded cycling (CON, N = 6).
Mona Esbjörnsson   +5 more
wiley   +1 more source

Early‐Life Betaine Supplementation Drives Sex‐Specific Metabolic Programming in Rats, Affecting FGF21 Signaling and Energy Balance

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
A maternal western diet (WD) and betaine supplementation during suckling influence metabolic programming. A maternal WD induced adverse metabolic effects in offspring, accompanied by altered FGF21‐related gene expression and decreased Akkermansia muciniphila abundance.
Rocío A. Martín‐Chamorro   +4 more
wiley   +1 more source

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