Results 81 to 90 of about 4,852 (215)

Dynamic Adaptation of Hematological Parameters, Albumin, and Non-Esterified Fatty Acids in Saddlebred and Standardbred Horses During Exercise

Animals
The response to exercise following a rest period may vary among horse breeds based on the importance of the hematological and hematochemical profiles of athletic horses.
Giuseppe Piccione, Francesca Arfuso, Elisabetta Giudice, Francesca Aragona, Pietro Pugliatti, Maria Francesca Panzera, Alessandro Zumbo, Vincenzo Monteverde, Vincenzo Bartolo, Adalberto Barbera, Claudia Giannetto   +10 more
doaj   +1 more source

Effect of Guanylic Acid on Plasma NEFA Response to Stress.

Experimental Biology and Medicine, 1960
SummaryPretreatment with hydrocortisone restores plasma NEFA response of adrenalectomized animals to normal but is without effect on intact rats. Pretreatment with guanylic acid, a purine nucleotide, abolishes NEFA response to fasting and tourniquet stress in the normal animal.
J, KABAL, E R, RAMEY
openaire   +2 more sources

Altering the Distribution of Daily Milk Allowance Pre‐Weaning Affects Growth Trajectories and Weaning Adaptation in Dairy‐Beef Calves

New Zealand Journal of Agricultural Research, Volume 69, Issue 6, December 2026.
Calf rearers commonly use restricted milk feeding to reduce costs, although providing more milk early in life may support early growth and calf welfare. This study compared two restricted milk feeding regimens that offered the same amount of calf milk replacer (CMR) but differed in distribution during the rearing period.
D. Sapalya, R. Hickson, S. McCoard, N. Lopez‐Villalobos, N. Martín   +4 more
wiley   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11143-11177, December 2026.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding, Qing Liu, Qiong Luo, Xiaojun Yao, Xingxing Fan   +4 more
wiley   +1 more source

Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic ß-cells

, 2008
Both stimulatory and detrimental effects of NEFAS (non-esterified fatty acids) on pancreatic ß-cells have been recognized. Acute exposure of the pancreatic ß-cell to high glucose concentrations and/or saturated NEFAs results in a substantial increase in ...
Philip Newsholme (23305726), D. Keane (6983640)   +1 more
core   +2 more sources

Aflatoxin B1 Exacerbates Ketogenic Diet‐Induced Hepatic Oxidative Stress and Glucose and Lipid Metabolic Disturbances in Mice

Food Frontiers, Volume 7, Issue 6, November 2026.
AFB1 exposure aggravates KD‐associated hepatic oxidative stress, inflammation, and glucose and lipid metabolic disturbances in mice. These effects are accompanied by dysregulation of AMPK, mTOR, and PPAR‐γ signaling and extensive hepatic metabolic reprogramming. ABSTRACT Aflatoxin B1 (AFB1) is a widespread mycotoxin with severe hepatotoxicity.
Xueyuan Hu, Zhenjun Sun, Xiaojing Wang, Shaochun Liu, ZhenBang Ye, Xueshu Han, Yang Ni, Linlin Hou, Yongping Chen, Huanqi Liu   +9 more
wiley   +1 more source

Role of Lipoprotein-Bound NEFAs in Enhancing the Specific Activity of Plasma CETP in the Nephrotic Syndrome

, 1997
Plasma cholesteryl ester transfer protein (CETP) activity, evaluated by the transfer of radiolabeled cholesteryl esters from a tracer dose of tritiated HDL to the plasma apolipoprotein B–containing lipoproteins, was significantly higher in patients with ...
Christian Lallemant, Laurent Lagrost, Emmanuel Florentin, Anne Athias, Philippe Gambert, Sylvie Braschi, Guy Rostoker, David Masson, Claude Martin, Bernard Jacotot   +9 more
core   +1 more source

Supplementary Table 2

, 2020
The composition of fasting serum NEFAs profile in normal and HSD mice at 16 ...
Huimin Lu (8294064)
core   +1 more source

Lack of relationship between cord serum angiopoietin-like protein 4 (ANGPTL4) and lipolytic activity in human neonates born by spontaneous delivery.

PLoS ONE, 2013
BackgroundLigands of peroxisome-proliferator activated receptors (PPARs), such as non-esterified fatty acids (NEFAs), induce expression of angiopoietin-like protein 4 (ANGPTL4). Recently ANGPTL4 has been reported to be a mediator of intracellular adipose
Henar Ortega-Senovilla, Ute Schaefer-Graf, Katrin Meitzner, Kristof Graf, Michael Abou-Dakn, Emilio Herrera   +5 more
doaj   +1 more source

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, Volume 34, Issue 11, Page 2094-2108, November 2026.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source