Results 101 to 110 of about 68,495 (293)
Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review
Epileptic Disorders, EarlyView.Abstract Objective A systematic review was conducted to synthesize current anatomo‐clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence‐based guidance for interpreting this ictal semiology during presurgical evaluation.
Mihai Dragos Maliia +2 more
wiley +1 more source
Reconstructing the Areal Organization of the Neocortex of the First Mammals
, 2011 The fossil record indicates that early mammals had small brains with proportionately little neocortex. Here we consider what is known about the organization of the neocortex in species with the least expanded neocortex from 6 major clades of the ...
Jon H. Kaas
core +1 more source
Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]
, 2013 During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Richardson, Magnus J. E. +2 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective Traumatic brain injury (TBI) induces widespread and persistent neuroinflammation, which is increasingly recognized as a key contributor to chronic sequelae including posttraumatic epilepsy (PTE), cognitive deficits, and neuropsychiatric disturbances. However, reliable biomarkers for identifying individuals at risk for these long‐term
Mohit Javalgekar +14 more
wiley +1 more source
Perils and progress in epilepsy surgery utilization: Twenty‐five years later
Epilepsia, EarlyView.Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley +1 more source
TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia
CNS Neuroscience &Therapeutics, EarlyView., 2023 Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi +19 more
wiley +1 more source
Frontiers in Neuroanatomy, 2018 The neocortex is the most complex part of the mammalian brain and as such it has undergone tremendous expansion during evolution, especially in primates.
Sebastian Römer +6 more
doaj +1 more source
The Origins of Neocortex: Connections and Lamination as Distinct Events in Evolution
, 1989 In the nonmammalian telencephalon, there are neuronal populations corresponding to cell groups in the neocortex of mammals in terms of connections, single unit-responses, chemical content, and functions.
Karten, Harvey J., Shimizu, Toru
core +1 more source
Epilepsia, EarlyView.Abstract Objective In status epilepticus there are concerns that the prolonged high‐intensity electrographic seizure activity causes neuronal death and poorer outcomes. In animal models of status epilepticus, early treatment that stops the seizures prevents the later development of epilepsy.
Yue Chen +2 more
wiley +1 more source
Multiple Origins of Neocortex: Contributions of the Dorsal Ventricular Ridge
, 1991 The uniqueness of mammalian neocortex may ultimately only be clarified with improved understanding of the evolutionary origins of cortical structure and cortical functions.
Harvey J. Karten +3 more
core +1 more source