Results 71 to 80 of about 15,453,746 (203)
Basal Progenitor Morphology and Neocortex Evolution.
, 2020 The evolutionary expansion of the mammalian neocortex is widely considered to be a basis of increased cognitive abilities. This expansion is a consequence of the enhanced production of neurons during the fetal/embryonic development of the neocortex ...
Kalebic, N., Huttner, W.
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Human Cerebral Cortex Cajal-Retzius Neuron: Development, Structure and Function. A Golgi Study
Frontiers in Neuroanatomy, 2015 The development, morphology and possible functional activity of the Cajal-Retzius cell of the developing human cerebral cortex have been explored herein. The C-RC, of extracortical origin, is the essential neuron of the neocortex first lamina.
Miguel eMarín-Padilla
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Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex. [PDF]
PLoS ONE, 2014 Neural precursor cells (NPCs) in the neocortex exhibit a high proliferation capacity during early embryonic development and give rise to cortical projection neurons after maturation.
Ryohei Minamide +3 more
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Frontiers in Genetics, 2014 A mechanistic understanding of the pathophysiology underpinning psychiatric disorders is essential for the development of targeted molecular therapies.
Steven eColvin, Kenneth Yu-Chung Kwan
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The enhancer landscape during early neocortical development reveals patterns of dense regulation and co-option. [PDF]
PLoS Genetics, 2013 Genetic studies have identified a core set of transcription factors and target genes that control the development of the neocortex, the region of the human brain responsible for higher cognition. The specific regulatory interactions between these factors,
Aaron M Wenger +7 more
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Neocortical development as an evolutionary platform for intragenomic conflict
Frontiers in Neuroanatomy, 2013 Embryonic development in mammals has evolved a platform for genomic conflict between mothers and embryos and, by extension, between maternal and paternal genomes.
Eric eLewitus, Alex T. Kalinka
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Cell Reports, 2013 During development of the embryonic neocortex, tightly regulated expansion of neural stem cells (NSCs) and their transition to intermediate progenitors (IPs) are critical for normal cortical formation and function.
Shan Bian +7 more
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Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling
Frontiers in Neural Circuits, 2013 During development, axons form branches in response to extracellular molecules. Little is known about the underlying molecular mechanisms. Here, we investigate how neurotrophin-induced axon branching is related to synaptic vesicle cycling for ...
Björn eGranseth +5 more
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Primate neocortex development and evolution: Conserved versus evolved folding.
, 2019 The neocortex, the seat of higher cognitive functions, exhibits a key feature across mammalian species-a highly variable degree of folding. Within the neocortex, two distinct subtypes of cortical areas can be distinguished, the isocortex and the ...
Vaid, S. +5 more
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Coupling between neurons of the developing rat neocortex [PDF]
The Journal of Neuroscience, 1983 We have estimated the prevalence of coupling between neurons of the rat neocortex during postnatal development. Single intracellular injections of the fluorescent dye Lucifer Yellow CH resulted in dye coupling among 70% of neurons from 1 to 4 days of age.
B W, Connors, L S, Benardo, D A, Prince
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