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Development Effectiveness Overview (DEO) 2020
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
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Summary: Histone methylation is essential for regulating gene expression during organogenesis to maintain stem cells and execute a proper differentiation program for their descendants.
Liang Li +14 more
doaj +1 more source
Recent advances in understanding neocortical development [version 1; peer review: 2 approved]
The neocortex is the largest part of the mammalian brain and is the seat of our higher cognitive functions. This outstanding neural structure increased massively in size and complexity during evolution in a process recapitulated today during the ...
Victor Borrell
doaj +1 more source
Modulation of Intrinsic Circuits in Developing Neocortex [PDF]
Numerous experimental studies have indicated that the developing rat brain is very susceptible to seizures. Immature rats have a low threshold for flurothyland kainic acid-induced seizures. Additionally, prolonged epileptiform activity is observed in slices of immature rat brain exposed to convulsant drugs in vitro.
openaire +2 more sources
Laminar and Temporal Expression Dynamics of Coding and Noncoding RNAs in the Mouse Neocortex
The hallmark of the cerebral neocortex is its organization into six layers, each containing a characteristic set of cell types and synaptic connections. The transcriptional events involved in laminar development and function still remain elusive.
Sofia Fertuzinhos +7 more
doaj +1 more source
Introduction. Convalescent COVID-19 patients have various signs of central nervous system damage, including those directly associated with SARS-CoV-2. Hence, studies of SARS-COV-2 related morphological changes in neocortex are particularly relevant for ...
Natal’ya M. Paramonova +7 more
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Development Effectiveness Overview (DEO) 2020: Executive Summary
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core +1 more source
Neocortex development depends on neural stem cell proliferation, cell differentiation, neurogenesis, and neuronal migration. Cytoskeletal regulation is critical for all these processes, but the underlying mechanisms are only poorly understood.
Pipicelli, F. +7 more
core +1 more source
Tcf7L2 is essential for neurogenesis in the developing mouse neocortex [PDF]
AbstractGeneration of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells in the ventricular zone and for differentiation of intermediate progenitors in the subventricular zone.
Olga Chodelkova +4 more
openaire +4 more sources
Layer Specific Development of Neocortical Pyramidal to Fast Spiking Cells Synapses.
All cortical neurons are engaged in inhibitory feedback loops which ensure excitation-inhibition balance and are key elements for the development of coherent network activity.
Olga eVoinova +6 more
doaj +1 more source

