Results 31 to 40 of about 15,453,746 (203)

Inter-American Development Bank Sustainability Report 2019 [PDF]

, 2020
Sustainability is a core element of the IDBs work. Long-term economic growth, and the reduction of poverty and inequality in Latin America and the Caribbean depend on development that is economically, financially, environmentally, socially, and ...
Inter-American Development Bank
core   +1 more source

Hedgehog signaling is involved in development of the neocortex [PDF]

Development, 2008
Sonic hedgehog (Shh) function is essential for patterning and cell fate specification, particularly in ventral regions of the central nervous system. It is also a crucial mitogen for cerebellar granule neuron precursors and is important in maintenance of the stem cell niche in the postnatal telencephalon.
Munekazu, Komada, Hirotomo, Saitsu, Masato, Kinboshi, Takashi, Miura, Kohei, Shiota, Makoto, Ishibashi   +5 more
openaire   +2 more sources

Inter-American Development Bank Annual Report 2021: Financial Statements

, 2022
This report is the second of two volumes which together constitute the Inter-American Development Bank\u27s 2021 Annual Report. This report contains the management\u27s discussion and analysis of the Bank\u27s ordinary capital and financial ...
Inter-American Development Bank
core   +1 more source

Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

eLife, 2018
The evolutionary increase in size and complexity of the primate neocortex is thought to underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene that, based on its expression pattern in fetal human neocortex and progenitor ...
Nereo Kalebic, Carlotta Gilardi, Mareike Albert, Takashi Namba, Katherine R Long, Milos Kostic, Barbara Langen, Wieland B Huttner   +7 more
doaj   +1 more source

Neural Progenitors in the Developing Neocortex of the Northern Tree Shrew (Tupaia belangeri) Show a Closer Relationship to Gyrencephalic Primates Than to Lissencephalic Rodents

Frontiers in Neuroanatomy, 2018
The neocortex is the most complex part of the mammalian brain and as such it has undergone tremendous expansion during evolution, especially in primates.
Sebastian Römer, Hannah Bender, Wolfgang Knabe, Elke Zimmermann, Rudolf Rübsamen, Johannes Seeger, Simone A. Fietz   +6 more
doaj   +1 more source

Genetic Mechanisms Underlying Cortical Evolution in Mammals

Frontiers in Cell and Developmental Biology, 2021
The remarkable sensory, motor, and cognitive abilities of mammals mainly depend on the neocortex. Thus, the emergence of the six-layered neocortex in reptilian ancestors of mammals constitutes a fundamental evolutionary landmark.
Lucía Florencia Franchini
doaj   +1 more source

A multi-resource data integration approach: Identification of candidate genes regulating cell proliferation during neocortical development

Frontiers in Neuroscience, 2014
Neurons of the mammalian neocortex are produced by proliferating cells located in the ventricular zone (VZ) lining the lateral ventricles. This is a complex and sequential process, requiring precise control of cell cycle progression, fate commitment and ...
Cynthia M Vied, Florian eFreudenberg, Yuting eWang, Alexandre A.S.F. Raposo, David eFeng, Richard S. Nowakowski   +5 more
doaj   +1 more source

Isolation of genetically manipulated neural progenitors and immature neurons from embryonic mouse neocortex by FACS

STAR Protocols, 2021
Summary: The embryonic mammalian neocortex includes neural progenitors and neurons at various stages of differentiation. The regulatory mechanisms underlying multiple aspects of neocortical development—including cell division, neuronal fate commitment ...
Yusuke Kishi, Yukiko Gotoh
doaj   +1 more source

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex

eLife, 2018
Understanding the molecular basis that underlies the expansion of the neocortex during primate, and notably human, evolution requires the identification of genes that are particularly active in the neural stem and progenitor cells of the developing ...
Marta Florio, Michael Heide, Anneline Pinson, Holger Brandl, Mareike Albert, Sylke Winkler, Pauline Wimberger, Wieland B Huttner, Michael Hiller   +8 more
doaj   +1 more source

Development Effectiveness Overview (DEO) 2023

, 2023
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source