Results 41 to 50 of about 15,453,746 (203)
The role of adherens junctions in the developing neocortex [PDF]
Cell Adhesion & Migration, 2015 The disproportional enlargement of the neocortex through evolution has been instrumental in the success of vertebrates, in particular mammals. The neocortex is a multilayered sheet of neurons generated from a simple proliferative neuroepithelium through a myriad of mechanisms with substantial evolutionary conservation.
Adam M, Stocker, Anjen, Chenn
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Neocortex expansion is linked to size variations in gene families with chemotaxis, cell–cell signalling and immune response functions in mammals [PDF]
Open Biology, 2016 Increased brain size is thought to have played an important role in the evolution of mammals and is a highly variable trait across lineages. Variations in brain size are closely linked to corresponding variations in the size of the neocortex, a distinct ...
Atahualpa Castillo-Morales +4 more
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The Molecular and Genetic Mechanisms of Neocortex Development [PDF]
Clinics in Perinatology, 2009 This article reviews key recent findings in the field of human cortical development. This development is divided into three major time-dependent phases: neural proliferation of inhibitory and excitatory neurons in spatially distinct regions, migration through multiple cellular boundaries, and maturation through morphologic changes that result in the ...
Alejandro L, Diaz, Joseph G, Gleeson
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Development of the human neocortex
Journal of Anatomy, 2010 Even a casual survey of the agenda of the scientific meetings and tables of contents in the major journals reveals that current research on cortical development is heavily biased towards rodents, particularly mice. Indeed our understanding of mouse genetics and development has been immensely enhanced by the use of mice with spontaneous mutations and ...
Gavin Clowry, Zoltán Molnár
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Frontiers in Neuroscience, 2015 The mammalian neocortex is a remarkable structure that is characterized by tangential surface expansion and six-layered lamination. However, how the mammalian neocortex emerged during evolution remains elusive.
Tadashi eNomura +4 more
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Frontiers in Neuroanatomy, 2021 Mammals are born on a precocial–altricial continuum. Altricial species produce helpless neonates with closed distant organs incapable of locomotion, whereas precocial species give birth to well-developed young that possess sophisticated sensory and ...
Mirjam Kalusa +4 more
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Renewed focus on the developing human neocortex
Journal of Anatomy, 2010 AbstractMany specifically human psychiatric and neurological conditions have developmental origins. Rodent models are extremely valuable for the investigation of brain development, but cannot provide insight into aspects that are specifically human. The human brain, and particularly the cerebral cortex, has some unique genetic, molecular, cellular and ...
Clowry, G, Molnár, Z, Rakic, P
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IDB Group Selected Development Contributions 2016-2019
, 2020 This infographic shows selected IDB Group\u27s contributions to the Sustainable Development Goals (SDGs) reported through the Group\u27s Corporate Results Framework between 2016 and ...
Inter-American Development Bank
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Cell Reports, 2019 Summary: To facilitate efficient oxygen and nutrient delivery, blood vessels in the brain form three-dimensional patterns. However, little is known about how blood vessels develop stereographically in the neocortex and how they control the expansion and ...
Mariko Komabayashi-Suzuki +15 more
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Cell Reports, 2020 Summary: The six-layered neocortex is a shared characteristic of all mammals, but not of non-mammalian species, and its formation requires an inside-out pattern of neuronal migration.
Tadashi Nomura +4 more
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