Results 1 to 10 of about 2,682,293 (230)
EMBO JournalNeocortex expansion during evolution is linked to higher numbers of neurons, which are thought to result from increased proliferative capacity and neurogenic potential of basal progenitor cells during development.
Mareike Albert +2 more
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Human-specific morphoregulatory signatures in basal radial glia characterise neocortex evolution [PDF]
Nat CommunAs the seat of our cognition, the human neocortex is an object of immense fascination. Human neocortex expansion during evolution has been attributed to an increase in the proliferative capacity of neural progenitor cells during development, particularly
Schütze T +22 more
europepmc +2 more sources
Frontiers in Cell and Developmental Biology, 2021 The neocortex, a six-layer neuronal brain structure that arose during the evolution of, and is unique to, mammals, is the seat of higher order brain functions responsible for human cognitive abilities.
Wieland B Huttner, Samir Vaid
exaly +3 more sources
The Ferret as a Model System for Neocortex Development and Evolution
Frontiers in Cell and Developmental Biology, 2021 The neocortex is the largest part of the cerebral cortex and a key structure involved in human behavior and cognition. Comparison of neocortex development across mammals reveals that the proliferative capacity of neural stem and progenitor cells and the ...
Nereo Kalebic
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Synaptic transmission in supragranular layers of the human cortex - comparative review of structure, function, and plasticity. [PDF]
Front Synaptic NeurosciSynapses are the highly specialized connection sites between neurons enabling the establishment of complex neuronal networks. As highly plastic structures, synapses collocate both the transmission and storage of information, which is an essential ...
Eichler A, Kruse P, Schob C, Lenz M.
europepmc +2 more sources
The evolution of human-type consciousness - a by-product of mammalian innovation mechanism - a preliminary hypothesis. [PDF]
Front PsycholHuman consciousness is often viewed as one of the pinnacles of evolution, with most theories positioning it as an upgrade of pre-existing cognitive skills.
Ben Zvi U.
europepmc +2 more sources
Human dexterity and brains evolved hand in hand. [PDF]
Commun BiolLarge brains and dexterous hands are considered pivotal in human evolution, together making possible technology, culture and colonisation of diverse environments. Despite suggestions that hands and brains coevolved, evidence remains circumstantial. Here,
Baker J, Barton RA, Venditti C.
europepmc +2 more sources
Generation of a homozygous ARHGAP11B knockout hiPSC line by CRISPR/Cas9 system
Stem Cell Research, 2022 The human specific gene ARHGAP11B is preferentially expressed in neural progenitors of fetal neocortex and plays a key role in the evolutionary expansion of the neocortex.
Yu Liu +12 more
doaj +1 more source
Neocortex expansion is linked to size variations in gene families with chemotaxis, cell–cell signalling and immune response functions in mammals [PDF]
Open Biology, 2016 Increased brain size is thought to have played an important role in the evolution of mammals and is a highly variable trait across lineages. Variations in brain size are closely linked to corresponding variations in the size of the neocortex, a distinct ...
Atahualpa Castillo-Morales +4 more
doaj +1 more source
Frontiers in Neuroanatomy, 2021 Mammals are born on a precocial–altricial continuum. Altricial species produce helpless neonates with closed distant organs incapable of locomotion, whereas precocial species give birth to well-developed young that possess sophisticated sensory and ...
Mirjam Kalusa +4 more
doaj +1 more source