Results 181 to 190 of about 2,682,293 (230)
ATP1B2 and GLAST identify two astrocyte subpopulations in the hippocampus with distinct molecular signatures. Transcriptomic shifts during aging differ between both subpopulations. Aged ATP1B2+ astrocytes rewire their metabolism while double‐positive aged astrocytes display a reduced synaptogenic capability.
Lucía Casares‐Crespo +6 more
wiley +1 more source
Evolutionary Pathways in Brain Morphology, Development, and Behavior in the Primate Lineage.
Raia P, Melchionna M.
europepmc +1 more source
How does the cerebellum contribute to cognitive functions? [PDF]
Diedrichsen J, McDougle SD.
europepmc +1 more source
Mental Scene and Memory Construction and the Hippocampus
ABSTRACT A neurocomputational theory of scene and memory construction during memory recall, prospective thinking, and autobiographical memory is described. The theory describes the nature of the representation of scenes using spatial view cells in a continuous attractor network in the medial parahippocampal cortex, and how the location in the scene ...
Edmund T. Rolls
wiley +1 more source
Progenitor diversity during formation of the mammalian neocortex. [PDF]
Atak Z, Haydar TF.
europepmc +1 more source
Mapping Projectome Heterogeneity of Subiculum Neuron Cell Types
ABSTRACT The subiculum (SUB) is the main output structure of the hippocampus, influencing diverse behaviors through its widespread cortical and subcortical connections. Our previous work creating the mouse Hippocampus Gene Expression Atlas (HGEA) identified four genetically distinct cellular layers across five columnar domains in the SUB, with gene ...
Ann W. Saustad, Michael S. Bienkowski
wiley +1 more source
Deviance detection via competitive inhibition between local neocortical ensembles. [PDF]
Thorpe RV, Moore CI, Jones SR.
europepmc +1 more source
ABSTRACT According to the functional ensemble of temperament (FET) model, individual differences in temperament arise from the balance of neurotransmitter systems also crucial for regulating circadian rhythms and sleep, suggesting a strong neurobiological link between temperament and sleep behavior.
Stefano Lasaponara +6 more
wiley +1 more source
This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...
Junyi Liang +7 more
wiley +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source

