Results 51 to 60 of about 2,682,293 (230)
Subplate Neurons as an Organizer of Mammalian Neocortical Development
Frontiers in Neuroanatomy, 2020 Subplate neurons (SpNs) are one of the earliest born and matured neurons in the developing cerebral cortex and play an important role in the early development of the neocortex.
Chiaki Ohtaka-Maruyama
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Identification of genes involved in the evolution of human intelligence through combination of inter-species and intra-species genetic variations [PDF]
PeerJ, 2020 Understanding the evolution of human intelligence is an important undertaking in the science of human genetics. A great deal of biological research has been conducted to search for genes which are related to the significant increase in human brain volume
Mengjie Li, Wenting Zhang, Xiaoyi Zhou
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Embodied cognitive evolution and the cerebellum [PDF]
, 2012 Much attention has focused on the dramatic expansion of the forebrain, particularly the neocortex, as the neural substrate of cognitive evolution. However, though relatively small, the cerebellum contains about four times more neurons than the neocortex.
Barton, Robert A.
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Neuromorphic Devices and Computing for Sensing, Memory, and Control
Advanced Science, EarlyView.This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Advanced Science, EarlyView.Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu +16 more
wiley +1 more source
The evolution of the brain, the human nature of cortical circuits and intellectual creativity
Frontiers in Neuroanatomy, 2011 The tremendous expansion and the differentiation of the neocortex constitute two major events in the evolution of the mammalian brain. The increase in size and complexity of our brains opened the way to a spectacular development of cognitive and mental ...
Javier eDeFelipe +2 more
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A Reconfigurable Memristive Spiking Neuron Enabling Advanced Neuromorphic Computing
Advanced Science, EarlyView.Pek Jun Tiw and co‐workers develop a reconfigurable memristive neuron that can exhibit four spiking behaviors with freely tunable spike train parameters. The neuron supports multiplexed spike encoding of multiple pieces of information. It also supports advanced neural network strategies, such as neural heterogeneity and dynamic mode switching ...
Pek Jun Tiw +6 more
wiley +1 more source
The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development
Cell Reports, 2021 Summary: Fusion transcripts or RNAs have been found in both disordered and healthy human tissues and cells; however, their physiological functions in the brain development remain unknown. In the analysis of deposited RNA-sequence libraries covering early
Min-Yi Ou +6 more
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Role of mechanical morphogenesis in the development and evolution of the neocortex [PDF]
, 2018 International audienceDuring the short period of brain development, nature is able to build the only system we know capable of producing cognition, language, creativity, and consciousness.
Roberto Toro +5 more
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Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
Advanced Science, EarlyView.The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source