Results 131 to 140 of about 8,130 (203)

Intranasal Introduction of Fc-Fused Interleukin-7 Provides Long-Lasting Prophylaxis against Lethal Influenza Virus Infection [PDF]

Influenza A virus (IAV) infection frequently causes hospitalization and mortality due to severe immunopathology. Annual vaccination and antiviral drugs are the current countermeasures against IAV infection, but they have a limited efficacy against new ...
Ahn, SS, Choi, DH, Choi, JA, Choi, YW, Kang, MC, Kim, DJ, Lee, Seung-Woo, Namkoong, H, Park, KS, Park, SJ, Park, Y, SUNG, YOUNG CHUL, Surh, CD, Yoon, SW   +13 more
core   +1 more source

Serum albumin and its interaction with the neonatal Fc receptor (FcRn) : characterization of the albumin/FcRn-binding mechanism

, 2013
In the past a lot of different biomolecular therapeutics were developed. A common problem using small molecules in therapy is their reduced serum concentration after short time period. The human body clears therapeutic molecules which have a size beneath the kidney clearance threshold in minutes to hours.
openaire   +2 more sources

Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis. [PDF]

PLoS One, 2020
Dylewski JF, Tonsawan P, Garcia G, Lewis L, Blaine J.   +4 more
europepmc   +1 more source

La production de colostrum chez la brebis : évaluation de la variabilité de la concentration et de la masse d’immunoglobulines G1(IgG1) [PDF]

, 2013
Chez la brebis, la placentation syndesmochoriale impose une prise colostrale précoce et de qualité pour la survie de l’agneau. L’objectif de ces travaux était d’apporter des éléments de réponse sur la faisabilité d’un phénotypage rapide et peu couteux ...
Jacquet, Amélie, Rousset, Anne-Lise
core  

Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications [PDF]

, 2015
Colonna, Marco, et al,, Fuchs, Anja, Wilson, Timothy J   +3 more
core   +2 more sources

FcRn mediated IgG transport by retinal pigment epithelium cells [PDF]

, 2012
Jeroen Bastiaans, Kiki van Bilsen, Marion Kolijn, Martin van Hagen, Nicoline M Korthagen, Robert W Kuijpers, Willem A Dik   +6 more
core   +1 more source

Immunoglobulin G Receptors (FcγR), in Addition to Target-Antigen and Neonatal Fc Receptor (FcRn), Influence Rituximab Pharmacokinetics. [PDF]

Clin Pharmacokinet
Ternant D, Le Tilly O, Cartron G, Desvignes C, Bensalem A, Mulleman D, Bejan-Angoulvant T, Gouilleux-Gruart V, Paintaud G.   +8 more
europepmc   +1 more source

Demonstration of Functional Similarity of Proposed Biosimilar ABP 501 to Adalimumab [PDF]

, 2016

core   +1 more source

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics. [PDF]

MAbs, 2018
Piche-Nicholas NM, Avery LB, King AC, Kavosi M, Wang M, O'Hara DM, Tchistiakova L, Katragadda M.   +7 more
europepmc   +1 more source

Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin. [PDF]

J Biol Chem, 2017
Schmidt EGW, Hvam ML, Antunes F, Cameron J, Viuff D, Andersen B, Kristensen NN, Howard KA.   +7 more
europepmc   +1 more source