L-type voltage-dependent Ca2+ channels expression involved in pre-neoplastic transformation of breast cancer [PDF]
Surgical and Experimental Pathology, 2022 Background Intracellular Ca2+ levels can modulate several cellular functions, including proliferation and other processes found altered in neoplastic cells.
Flávia Aguiar +4 more
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MicroRNAs involved in neoplastic transformation of liver cancer stem cells [PDF]
Journal of Experimental & Clinical Cancer Research, 2010 Background The existence of cancer stem cells in hepatocellular carcinoma (HCC) has been verified by characterizing side population (SP) cells based on efflux of Hoechst 33342 dye from stem cells. Recent advances in microRNA (miRNA) biology have revealed
Wang Xinchuan +5 more
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Angiogenesis and neoplastic transformation of Barrett's epithelium
British Journal of Surgery, 2004 Angiogenesis has significance in neoplastic transformation, prognosis and future ...
H J Stein, C Möbius, Stein H J
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Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation
Neoplasia: An International Journal for Oncology Research, 2016 The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and ...
Yiannis Drosos +10 more
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Anabolic Steroids-Driven Regulation of Porcine Ovarian Putative Stem Cells Favors the Onset of Their Neoplastic Transformation [PDF]
International Journal of Molecular Sciences, 2021 Gabriela Gorczyca +2 more
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PLoS ONE, 2014 The leucine rich repeats and immunoglobulin-like protein 1 (LRIG1) is a newly discovered negative regulator of epidermal growth factor receptor (EGFR) and a proposed tumor suppressor.
Maho Nagata +5 more
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Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling
Cells, 2021 A single primary cilium projects from most vertebrate cells to guide cell fate decisions. A growing list of signaling molecules is found to function through cilia and control ciliogenesis, including the fibroblast growth factor receptors (FGFR). Aberrant
Alexandru Nita +3 more
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Adenomatoid Odontogenic Tumour Associated with Dentigerous Cyst: Case Report with Literature Review [PDF]
Journal of Clinical and Diagnostic Research, 2021 Adenomatoid Odontogenic Tumour (AOT) is a relatively uncommon benign odontogenic tumour composed of odontogenic epithelium in a variety of histoarchitectural patterns. Conventional AOT is predominantly seen in females in second decade of life exhibiting
Pradipta Ramgonda Patil +4 more
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Frontiers in Pharmacology, 2022 The cytoplasmic actin isoforms (β- and γ-actins) contribute greatly to cellular processes such as cel-cell and cell-matrix interactions, as well as cell polarization, motility and division. Distinct isoforms modulations are linked to serious pathologies,
V. B. Dugina +3 more
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Functions of BLM Helicase in Cells: Is It Acting Like a Double-Edged Sword?
Frontiers in Genetics, 2021 DNA damage repair response is an important biological process involved in maintaining the fidelity of the genome in eukaryotes and prokaryotes. Several proteins that play a key role in this process have been identified.
Ekjot Kaur, Ritu Agrawal, Sagar Sengupta
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