Results 21 to 30 of about 345,106 (211)

Functions of BLM Helicase in Cells: Is It Acting Like a Double-Edged Sword?

Frontiers in Genetics, 2021
DNA damage repair response is an important biological process involved in maintaining the fidelity of the genome in eukaryotes and prokaryotes. Several proteins that play a key role in this process have been identified.
Ekjot Kaur, Ritu Agrawal, Sagar Sengupta
doaj   +1 more source

Barrett's esophagus: The pathomorphological and molecular genetic keystones of neoplastic progression

Cancer Medicine, 2022
Barrett's esophagus is a widespread chronically progressing disease of heterogeneous nature. A life threatening complication of this condition is neoplastic transformation, which is often overlooked due to lack of standardized approaches in diagnosis ...
Ksenia S. Maslyonkina, Alexandra K. Konyukova, Darya Y. Alexeeva, Mikhail Y. Sinelnikov, Liudmila M. Mikhaleva   +4 more
doaj   +1 more source

Genome-wide screening of tumor suppressor genes in oncogenic transformation of normal lung epithelial cells and preliminary validation in sample databases

Di-san junyi daxue xuebao, 2022
Objective To identify new human lung cancer suppressors in a genome-wide screening library during neoplastic transformation of normal human lung epithelial cells using CRISPR/Cas9-mediated genome editing, and preliminarily validate the Results in non ...
ZHAO Binyu, ZHANG Junlei, WANG Jiaqi, RUAN Yan, ZHANG Yue, LIU Lianlian   +5 more
doaj   +1 more source

Mucoepidermoid Carcinoma Superimposed on a Warthin's Tumor: A Case Report and Review of the Literature [PDF]

Iranian Journal of Otorhinolaryngology, 2021
Introduction: Warthin's tumor (WT) is the second most common neoplasm of the parotid gland and consists of two components, including lymphoid stroma and glandular epithelium.
Shirin Taraz-Jamshidi, Samaneh Mahjouri, Leila Vazifeh-Mostaan   +2 more
doaj   +1 more source

Radiation-Induced Neoplastic Transformation , Hormesis and Risk Assessment

Dose-Response, 2007
Dose-response curves for various low-LET radiation sources have consistently been demonstrated to be J-shaped for the cancer-relevant endpoint of neoplastic transformation in vitro.
J. Leslie Redpath PhD, Eugene Elmore PhD
doaj   +1 more source

Campylobacter jejuni causes colorectal cancer

World Journal of Colorectal Surgery, 2022
The incidence of colorectal cancer (CRC) has drastically increased in several Asian countries during the past four decades. These rapid epidemiological variations suggest that environmental parameters contribute to neoplastic transformation within the ...
Pascal Alain Gervaz, Álvaro De Campos, Alberto Caeiro   +2 more
doaj   +1 more source

An unsuspected ameloblastoma in the subpontic region of the mandible with consideration of pathogenesis from the radiographic course

European Journal of Medical Research, 2010
The purpose of this report is to document a case of unsuspected ameloblastoma involving the right man dibular subpontic region in a 38-year-old Cambodian female patient. This lesion was purportedly preceded by multiple radiolucencies which were diagnosed
Siar CH, Nakano K, Chelvanayagam PI, Ng KH, Nagatsuka H, Kawakami T   +5 more
doaj   +1 more source

Mechanistic Basis for Nonlinear Dose-Response Relationships for Low-Dose Radiation-Induced Stochastic Effects

Dose-Response, 2003
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for humans. With the LNT model, any radiation exposure is assumed to increase one's risk of cancer.
Bobby R. Scott, Dale M. Walker, Yohannes Tesfaigzi, Helmut Schöllnberger, Vernon Walker   +4 more
doaj   +1 more source

Neoplastic potential of odontogenic cysts

Contemporary Clinical Dentistry, 2011
Odontogenic cysts and tumors are distinct entities and quite a common occurrence in the jaw bones. The lining of odontogenic cysts shows a potential for neoplastic transformation to non odontogenic malignancies like squamous cell carcinoma and ...
Zama Moosvi, S Amsavardani Tayaar, G S Kumar   +2 more
doaj   +1 more source

Histomorphological development and progression of gastric intramucosal papillary adenocarcinoma—a retrospective study

Frontiers in Oncology
ObjectiveThe aim of this study is to elucidate the developmental process, progression patterns, and histomorphological features of gastric-type intramucosal papillary adenocarcinoma.MethodsThis study employed a retrospective research method. Histological
Yang-Kun Wang, Xiong-Fei Zou, Wen-Yi Wang, Ying-Ying Li, Yan Zhong, Pei Guo, Tao Wang, Si-Liang Xu, Su-Nan Wang   +8 more
doaj   +1 more source