Results 21 to 30 of about 331,839 (297)

Barrett's esophagus: The pathomorphological and molecular genetic keystones of neoplastic progression

open access: yesCancer Medicine, 2022
Barrett's esophagus is a widespread chronically progressing disease of heterogeneous nature. A life threatening complication of this condition is neoplastic transformation, which is often overlooked due to lack of standardized approaches in diagnosis ...
Ksenia S. Maslyonkina   +4 more
doaj   +1 more source

Genome-wide screening of tumor suppressor genes in oncogenic transformation of normal lung epithelial cells and preliminary validation in sample databases

open access: yesDi-san junyi daxue xuebao, 2022
Objective To identify new human lung cancer suppressors in a genome-wide screening library during neoplastic transformation of normal human lung epithelial cells using CRISPR/Cas9-mediated genome editing, and preliminarily validate the Results in non ...
ZHAO Binyu   +5 more
doaj   +1 more source

Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles [PDF]

open access: yes, 1987
The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined
Fenn, S.   +5 more
core   +1 more source

DNA methylation and neoplastic transformation

open access: yes, 1989
DNA methylation at specific gene is deranged in neoplasia and a decrease in methylation of some genes is suggestive of neoplastic ...
HANAU, Stefania   +3 more
core   +2 more sources

Mucoepidermoid Carcinoma Superimposed on a Warthin's Tumor: A Case Report and Review of the Literature [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2021
Introduction: Warthin's tumor (WT) is the second most common neoplasm of the parotid gland and consists of two components, including lymphoid stroma and glandular epithelium.
Shirin Taraz-Jamshidi   +2 more
doaj   +1 more source

Clonal dynamics of progressive neoplastic transformation [PDF]

open access: yesProceedings of the National Academy of Sciences, 1999
In a recent study, we found that newly isolated clones of NIH 3T3 mouse cells undergo neoplastic transformation more readily than uncloned cultures from which they were derived. After eleven low-density passages (LDPs), most of the 29 clones produced lightly stained early-stage transformed foci when grown to confluence in a primary assay for ...
M, Chow, H, Rubin
openaire   +2 more sources

Campylobacter jejuni causes colorectal cancer

open access: yesWorld Journal of Colorectal Surgery, 2022
The incidence of colorectal cancer (CRC) has drastically increased in several Asian countries during the past four decades. These rapid epidemiological variations suggest that environmental parameters contribute to neoplastic transformation within the ...
Pascal Alain Gervaz   +2 more
doaj   +1 more source

Neoplastic transformation in longstanding fistula-in-ano [PDF]

open access: yesPostgraduate Medical Journal, 1987
Summary A case in which an infiltrating mucinous carcinoma developed within a suprasphincteric fistula-in-ano is presented. The diagnosis was suspected on biopsy and confirmed by repeat biopsy. The clinical and histological features of this case establish with certainty that the carcinoma arose within the fistula and was not a secondary ...
G H, Welch, I G, Finlay
openaire   +2 more sources

An unsuspected ameloblastoma in the subpontic region of the mandible with consideration of pathogenesis from the radiographic course

open access: yesEuropean Journal of Medical Research, 2010
The purpose of this report is to document a case of unsuspected ameloblastoma involving the right man dibular subpontic region in a 38-year-old Cambodian female patient. This lesion was purportedly preceded by multiple radiolucencies which were diagnosed
Siar CH   +5 more
doaj   +1 more source

Mechanistic Basis for Nonlinear Dose-Response Relationships for Low-Dose Radiation-Induced Stochastic Effects

open access: yesDose-Response, 2003
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for humans. With the LNT model, any radiation exposure is assumed to increase one's risk of cancer.
Bobby R. Scott   +4 more
doaj   +1 more source

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