Results 21 to 30 of about 383,457 (302)

Radiation-Induced Neoplastic Transformation , Hormesis and Risk Assessment

open access: yesDose-Response, 2007
Dose-response curves for various low-LET radiation sources have consistently been demonstrated to be J-shaped for the cancer-relevant endpoint of neoplastic transformation in vitro.
J. Leslie Redpath PhD, Eugene Elmore PhD
doaj   +1 more source

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. [PDF]

open access: yes, 2015
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic and inflammatory microenvironment that is formed primarily by activated, myofibroblast-like, stellate cells.
Dhall, Deepti   +4 more
core   +1 more source

Campylobacter jejuni causes colorectal cancer

open access: yesWorld Journal of Colorectal Surgery, 2022
The incidence of colorectal cancer (CRC) has drastically increased in several Asian countries during the past four decades. These rapid epidemiological variations suggest that environmental parameters contribute to neoplastic transformation within the ...
Pascal Alain Gervaz   +2 more
doaj   +1 more source

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

open access: yes, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D   +10 more
core   +1 more source

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. [PDF]

open access: yes, 2014
Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc).
Baffa, R   +17 more
core   +4 more sources

Mechanistic Basis for Nonlinear Dose-Response Relationships for Low-Dose Radiation-Induced Stochastic Effects

open access: yesDose-Response, 2003
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for humans. With the LNT model, any radiation exposure is assumed to increase one's risk of cancer.
Bobby R. Scott   +4 more
doaj   +1 more source

An unsuspected ameloblastoma in the subpontic region of the mandible with consideration of pathogenesis from the radiographic course

open access: yesEuropean Journal of Medical Research, 2010
The purpose of this report is to document a case of unsuspected ameloblastoma involving the right man dibular subpontic region in a 38-year-old Cambodian female patient. This lesion was purportedly preceded by multiple radiolucencies which were diagnosed
Siar CH   +5 more
doaj   +1 more source

Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]

open access: yes, 2018
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core   +1 more source

Suppression of Neoplastic Transformation by Low Doses of Low Let Radiation

open access: yesDose-Response, 2006
A major concern of exposure to low doses of radiation is the risk of cancer induction. Epidemiologic data are rarely powerful enough to accurately discriminate this risk at doses
J. Leslie Redpath PhD
doaj   +1 more source

ATF2 promotes urothelial cancer outgrowth via cooperation with androgen receptor signaling

open access: yesEndocrine Connections, 2018
We investigated the functional role of ATF2, a transcription factor normally activated via its phosphorylation in response to phospho-ERK/MAPK signals, in the outgrowth of urothelial cancer.
Satoshi Inoue   +7 more
doaj   +1 more source

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