Results 1 to 10 of about 8,276 (115)

Urinary neopterin concentrations vs total neopterins for clinical utility. [PDF]

Clinical Chemistry, 1989
Abstract Neopterin measurements are especially useful as an early marker in (e.g.) allograft rejections and in patients infected with human immunodeficiency virus type 1 (HIV-1). An increased concentration of total neopterins (neopterin + dihydroneopterin) is also a significant marker in patients with HIV-1 infection.
Fuchs, Dietmar, Milstien, Sheldon, Krämer, Alexander, Reibnegger, Gilbert, Werner, Ernst R., Goedert, James J., Kaufman, Seymour, Wachter, Helmut   +7 more
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Neopterin as an endogenous antioxidant [PDF]

FEBS Letters, 1992
The in vitro potency of neopterin (NP) as an antioxidant and its in vivo activity to suppress alloxan‐induced diabetes were investigated. The reduced form of neopterin, 5,6,7,8‐tetrahydroneopterin (NPH‐4), showed an extremely high superoxide anion radical scavenging activity in two assay systems, i.e.
Yoshio Kajiwara, Shuji Kojima, Takeshi Icho, Kazuhiko Kubota   +3 more
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Neopterin as Tumour Marker Serum and Urinary Neopterin Concentrations in Malignant Diseases [PDF]

Clinical Chemistry and Laboratory Medicine, 1986
Serum and urinary neopterin concentrations were measured in 142 patients suffering from various malignant diseases. Increased serum and urinary neopterin levels were found in 48% and 55% of patients respectively. Neopterin showed sufficient sensitivity in the detection of haematological disorders and hypernephroma, whereas the sensitivity of neopterin ...
Kuzmits, R., Ludwig, H., Legenstein, Elisabeth, Szekeresz, T., Kratzik, C., Hofbauer, J.   +5 more
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Neopterin in Septic Arthritis

Pteridines, 1995
Summary Despite its low incidence septic arthritis remains a serious problem in orthopaedic practice. General or local immunosuppression predisposes for septic arthritis. Thus we see an increasing incidence in elderly patients, in patients suffering from rheumatic diseases and after alloplastic arthroplasty of the hip and of the knee.
K. Koberg, S. Schälicke, B. Klosterhalfen, K.M. Peters   +3 more
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Neopterin in Clinical Use

Pteridines, 1989
Summary A brief review is given on the value of neopterin determination as a biochemical marker for the in vivo activation state of cell-mediated immunity. In a broad spectrum of diseases which are recognized or supposed to involve activation of monocytes/macrophages by interferon gamma derived from activated T lymphocytes, the applicability and ...
Helmut Wachter, Ernst R. Werner, Arno Hausen, Dietmar Fuchs, Gilbert Reibnegger   +4 more
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Neopterin measurement in clinical diagnosis [PDF]

Journal of Clinical Pharmacy and Therapeutics, 2001
Neopterin is a marker associated with cell-mediated immunity. It is produced in monocytes/macrophages primarily upon stimulation with interferon-gamma. Due to its chemical structure, neopterin belongs to the class of pteridines. It is excreted in an unchanged form via the kidneys. Serum levels above 10 nmol/L are regarded as elevated.
A Berdowska, K Zwirska-Korczala
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Neopterin—a forgotten biomarker

Journal of the American College of Cardiology, 2003
In a recent issue of the Journal, Blake and Ridker [(1)][1]summarized findings regarding the prognostic role of C-reactive protein (CRP) and other inflammatory markers in patients with acute coronary syndromes (ACS).
Pablo Avanzas, Juan Carlos Kaski, Ramón Arroyo-Espliguero   +2 more
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Neopterin in Patients with Choroidal Melanoma [PDF]

Clinical Chemistry and Laboratory Medicine, 1993
Neopterin excretion in urine and the serum concentrations of neopterin were compared in 101 patients with a malignant melanoma of the choroid and in a matched group of healthy volunteers. The majority of cases (n = 99) presented an untreated (n = 20) or treated and either partially (n = 33) or completely regressed (n = 47) melanoma of stage I-III ...
Gerding, H., Cremer-Bartels, G., Krause, K., Busse, H.   +3 more
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Neopterin in Bone Banking

Pteridines, 1998
Summary Not only in blood transfusion, but also in transplantation of allogenous bone, infection of patients with bacteria and especially with virus is possible. Neopterin as an unspecific marker of an activated cellmediated immune response is elevated in fresh viral infection even before antibodies are detectable. Additional determination of neopterin
K. M. Peters, B. Klosterhalfen
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Role for inflammatory markers in predicting right ventricular failure in mechanical assist device recipients

ESC Heart Failure, EarlyView.
Abstract Right ventricular failure (RVF) is a common complication following left ventricular assist device (LVAD) implantation and increases patient morbidity and mortality. Due to the complex and limited understanding of RVF pathophysiology, efforts to prognosticate RVF after LVAD have been challenging.
Abdul‐Fatawu Osman, Shane S. Scott, Ebubechukwu O. Ezeh, Evans Osuji, Israel O. Ailemen, Mohamed H. Derbala, Salil Kumar, Asvin M. Ganapathi, Daniel B. Sims, Ashrith Guha, Bryan A. Whitson, Sakima A. Smith   +11 more
wiley   +1 more source