Evaluating predictive markers for viral rebound and safety assessment in blood and lumbar fluid during HIV-1 treatment interruption [PDF]
, 2020 Background: Validated biomarkers to evaluate HIV-1 cure strategies are currently lacking, therefore requiring analytical treatment interruption (ATI) in study participants.
De Langhe, Nele +15 more
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Expansion of neopterin and beta2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection [PDF]
, 1992 Inhaltsverzeichnis ...
Bogner, Johannes R. +5 more
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Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. [PDF]
, 2016 BackgroundHuman immunodeficiency virus (HIV) and methamphetamine use commonly affect neurocognitive (NC) functioning. We evaluated the relationships between NC functioning and two fibroblast growth factors (FGFs) in volunteers who differed in HIV ...
Bharti, Ajay R +10 more
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Serum contents of immunoreactive pancreatic secretory trypsin inhibitor and seminal plasma acrosin-trypsin inhibitor in polytraumatized patients [PDF]
, 1990 2 ...
JJ Calvete +6 more
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Metabolomics Identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis [PDF]
, 2016 Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood and lymphatics whilst for stage 2, parasites are found beyond the
Barrett, Michael P. +7 more
core +4 more sources
Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial. [PDF]
, 2017 More efficacious treatment regimens are needed for tuberculosis, however, drug development is impeded by a lack of reliable biomarkers of disease severity and of treatment effect. We conducted a directed screen of host biomarkers in participants enrolled
Barbero, S +14 more
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The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]
, 2017 Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George +2 more
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Inflammation and endothelial function: Direct vascular effects of human C-reactive protein on nitric oxide bioavailability [PDF]
, 2005 Background - Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when vascular reactivity may be modulated.
Clapp, BR +10 more
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Cerebrospinal fluid neopterin analysis in neuropediatric patients: establishment of a new cut off-value for the identification of inflammatory-immune mediated processes [PDF]
, 2018 OBJECTIVE: A high level of cerebrospinal fluid (CSF) neopterin is a marker of central nervous system inflammatory-immune mediated processes. We aimed to assess data from 606 neuropediatric patients, describing the clinical and biochemical features of ...
Artuch Iriberri, Rafael +8 more
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Neopterin as an Endogenous Antioxidant.
Eisei kagaku, 1995 The in vitro antioxidative activity of neopterin and its in vivo potency to suppress gastric ischemia were investigated. The scavenging activity of the reduced form of neopterin, 5,6,7,8-tetrahydroneopterin (NPH4), against superoxide anion radicals, showed an extremely high superoxide anion radical scavenging activity in two assay systems, i.e ...
openaire +4 more sources