Results 21 to 30 of about 8,276 (115)
Epilepsia Open, EarlyView.Abstract Dravet syndrome (DS) is an early onset, developmental, and epileptic encephalopathy characterized by drug‐resistant seizures and multiple comorbidities. It has been reported that in adulthood, it may be accompanied by parkinsonism, but the pathogenesis of this condition remains unclear.
Ryo Sugiyama +5 more
wiley +1 more source
Urinary Neopterin in Malignant Lymphoma
The International Journal of Biological Markers, 1991 Urinary neopterin levels were studied in 96 patients with malignant lymphomas. Twenty-eight had Hodgkin's disease and 68 non-Hodgkin's lymphoma. Neopterin excretion was significantly related to the clinical stage of the disease. Mean neopterin excretion in patients with active disease (634 ± 527 μmol neopterin/mol creatinine) was significantly higher (
PICCININI, Lino +4 more
openaire +4 more sources
Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals
Journal of Hospital Medicine, EarlyView.Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta +8 more
wiley +1 more source
Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]
, 1994 Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O. +6 more
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Efficient Total Syntheses of Natural Neopterin Glycosides: Neopterin Glucronide and Solfapterin [PDF]
HETEROCYCLES, 2017 1’,2’-Di-O-acetyl-N2-(N,N-dimethylaminomethylene)-3-[2-(4-nitro- phenyl)ethyl]neopterin (11a) and its 1’,2’-di-O-benzoyl analog (11b) were prepared from neopterin in 5 steps, respectively. Glycosylation of 11a with methyl 2,3,4-tri-O-benzoyl-α-D-glucopyranosyluronate bromide (15b) in the presence of silver triflate afforded the corresponding 3’-O-(β-D ...
Hanaya, Tadashi +3 more
openaire +3 more sources
Developmental Medicine &Child Neurology, EarlyView.Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes +6 more
wiley +1 more source
European Journal of Neurology, Volume 32, Issue 6, June 2025.ABSTRACT Background New‐onset refractory status epilepticus (NORSE) is a diagnostically challenging and severe epileptic presentation in which aetiology is an important predictor of outcome. This retrospective study aimed to investigate the utility of metabolic screening to determine the underlying cause in 42 patients with suspected NORSE, admitted to
Jennifer Kilmer +6 more
wiley +1 more source
Arthritis &Rheumatology, Volume 77, Issue 5, Page 506-520, May 2025.Clinical tools that can aid in the diagnostic differentiation of juvenile dermatomyositis from muscular dystrophy.
Jacqueline A. Madison +9 more
wiley +1 more source
The role of Neopterin in cardiovascular disease
Monaldi Archives for Chest Disease, 2016 Inflammation plays a key role in the initiation and progression of atherosclerosis but also in the pathophysiology of atheromatous plaque disruption and the development of acute coronary syndromes. Neopterin is a marker of inflammation and of immune system activation, it is synthesized by macrophages, that, once activated, release this substance ...
Pacileo, M. +9 more
openaire +5 more sources
Acta Physiologica, Volume 241, Issue 5, May 2025.Abstract Aim Recent pre‐clinical evidence suggests that the tryptophan metabolite 3‐hydroxyanthranilic acid (3‐HAA) and the related enzyme activity along the kynurenine metabolic pathway (KP) are associated with lifespan extension. We aimed to translate these findings into humans and expose exercise training as a potential non‐pharmacological ...
Niklas Joisten +10 more
wiley +1 more source