Results 21 to 30 of about 22,017 (305)

The Role of Neopterin and Interleukin-6 Detection in Saliva and Plasma in Oral and Oropharyngeal Cancer Patients: A Prospective Study. [PDF]

open access: yesClin Exp Dent Res
ABSTRACT Objectives The incidence of oral and oropharyngeal cancer is continually rising and affects increasingly younger patients. Consequently, many studies focus on early diagnosis using appropriate biomarkers. Neopterin and interleukin‐6 (IL‐6) are promising predictive and prognostic markers of immune response activation, both systemic and local ...
Šašková L   +8 more
europepmc   +2 more sources

Neopterin, the Cell-Mediated Immune Response Biomarker, in Inflammatory Periodontal Diseases: A Narrative Review of a More than Fifty Years Old Biomarker

open access: yesBiomedicines, 2023
Neopterin is a biomarker of the activation of cellular immunity. The purpose of this review is to summarise neopterin metabolism, methods of its detection, and its role in inflammation, focusing on periodontal inflammatory diseases.
Ondřej Heneberk   +2 more
semanticscholar   +1 more source

Role of neopterin as an inflammatory biomarker in congestive heart failure with insights on effect of drug therapies on its level

open access: yesInflammoPharmacology, 2022
Inflammation has a major role in the pathogenesis of heart failure (HF). It triggers a cascade that leads to the release of pro-inflammatory cytokines which in turn cause cardiac hypertrophy, fibrosis, apoptosis, negative inotorpy and leukocyte ...
G. Dogheim   +2 more
semanticscholar   +1 more source

Urinary neopterin reflects immunological variation associated with age, helminth parasitism, and the microbiome in a wild primate

open access: yesScientific Reports, 2022
Neopterin, a product of activated white blood cells, is a marker of nonspecific inflammation that can capture variation in immune investment or disease-related immune activity and can be collected noninvasively in urine.
India A. Schneider-Crease   +17 more
semanticscholar   +1 more source

Concentrations of urinary neopterin, but not suPAR, positively correlate with age in rhesus macaques

open access: yesFrontiers in Ecology and Evolution, 2022
Identifying biomarkers of age-related changes in immune system functioning that can be measured non-invasively is a significant step in progressing research on immunosenescence and inflammaging in free-ranging and wild animal populations.
Eve B. Cooper   +7 more
semanticscholar   +1 more source

Elevated Neopterin Levels Predict Fatal Outcome in SARS-CoV-2-Infected Patients

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Highlights Innate immune activation during Covid-19 infection is associated with pernicious clinical outcome. Background Coronavirus disease 2019 (Covid-19) is a worldwide threat that has already caused more than 3 000 000 deaths.
M. Chauvin   +19 more
semanticscholar   +1 more source

Neopterin, procalcitonin, clinical biochemistry, and hematology in calves with neonatal sepsis

open access: yesTropical Animal Health and Production, 2021
This study aims to determine how neopterin, procalcitonin, biochemical and hematological parameters change during treatment of calves with neonatal sepsis. A total of 25 calves divided into two groups.
E. Akyüz, G. Gökçe
semanticscholar   +1 more source

Urinary neopterin: A novel biomarker of disease progression in amyotrophic lateral sclerosis

open access: yesEuropean Journal of Neurology, 2021
The aim was to evaluate urinary neopterin, a marker of pro‐inflammatory state, as a potential biomarker of disease prognosis and progression in amyotrophic lateral sclerosis (ALS); and to compare its utility to urinary neurotrophin receptor p75 ...
Stephanie R Shepheard   +9 more
semanticscholar   +1 more source

Clues to Disease Activity in Juvenile Dermatomyositis: Neopterin and Other Biomarkers

open access: yesDiagnostics, 2021
Easily accessible biomarkers are urgently needed to evaluate immune activation in Juvenile Dermatomyositis (JDM). The goal of this retrospective study is to define immunological and clinical differences between untreated JDM patients with either normal ...
Amer M. Khojah   +2 more
semanticscholar   +1 more source

Urinary neopterin of wild chimpanzees indicates that cell-mediated immune activity varies by age, sex, and female reproductive status

open access: yesScientific Reports, 2021
The study of free-living animal populations is necessary to understand life history trade-offs associated with immune investment. To investigate the role of life history strategies in shaping proinflammatory cell-mediated immune function, we analyzed age,
Jacob D. Negrey   +3 more
semanticscholar   +1 more source

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