Results 21 to 30 of about 769 (50)

Association Between Neopterin Production and other Parameters in a Population of Blood Donors

Pteridines, 2002
Neopterin is released from human monocyte-derived macrophages preferentially upon stimulation with the Thlcell cytokine interferon-γ. In humans, increased concentrations of neopterin in serum and urine have been found in viral infections including human ...
Schennach Harald, Murr Christian, Gächter Elmar, Mayersbach Peter, Schönitzer Diether, Fuchs Dietmar   +5 more
doaj   +1 more source

Systemic Immune Activation, Anemia and Thrombocytosis in Breast Cancer Patients Treated by Doxorubicin and Paclitaxel

Pteridines, 2006
Increased urinary concentrations of neopterin, an indicator of systemic immune activation, have been reported only in a minority of patients with breast cancer. We determined urinary neopterin by high-performance liquid chromatography in 78 patients with
Melichar Bohuslav, Solichova Dagmar, Melicharova Karolina, Urminska Hana, Ryska Ales, Cermanova Melanie   +5 more
doaj   +1 more source

The relationship between plasma level of indoleamine 2,3-dioxygenase and neopterin in patients with depression

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Preliminary results of the study that intended to compare serum indoleamine 2,3-dioxygenase (IDO) and neopterin levels in patients with major depression and the healthy control group is presented.
Adem Balıkcı, Murat Erdem, Abdullah Bolu, Tuncer Çaycı, Emre Aydemir, A. Gazi Ünlü, Emin Özgür Akgül   +6 more
doaj  

The Effects of Neopterin on the Viability and Motility of Different HCC Cell Lines

Proceedings, 2018
Increased neopterin levels reflect the activation of the cellular immune system which is of importance in the pathogenesis and progression of various diseases such as cancer.
Imge Kunter, Marianna Najjar, Yelin Subasi, Niloofar Zabib, Gonul Sahin   +4 more
doaj   +1 more source

Plasma total neopterin and neopterin levels are significantly elevated in stroke patients before carotid endarterectomy surgery

Pteridines
Atherosclerosis is an inflammatory disease where activated immune cells are recruited into the artery wall forming artery plaques. Interferon-γ released by T-cells causes macrophage synthesis and release of 7,8-dihydroneopterin, an antioxidant and CD36 ...
Raajasekar Siddarth, Roake Justin, Cameron Vicky, Benson Ruth, Pilbrow Anna, Gieseg Steven   +5 more
doaj   +1 more source

Neopterin Concentrations in Colon Dialysate

Pteridines, 2001
Increased production of neopterin in humans is indicative for an activated cellular immune response. The intestinal immune system encounters an enormous amount of infectious agents or injurious substances evoking a cellular immune response. The objective
Ledjeff E., Artner-Dworzak E., Witasek A., Fuchs D., Hausen A.   +4 more
doaj   +1 more source

Influence of Three Different Diet Modes Combined with Exercise Loads on Urinary and Plasma Neopterin Concentrations: A Longitudinal Study

Pteridines, 1997
During six months, we studied the influence of three extremely different diet modes (normal diet, carbohydrate- rich diet, fat-rich diet) combined with three defined exercise loads (step test, endurance test fo r 30 minutes, endurance test for 90 minutes)
Lamprecht Manfred, Mlekusch Walter, Vrecko Karoline, Reibnegger Gilbert   +3 more
doaj   +1 more source

Neopterin Counters Vascular Inflammation and Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundNeopterin, a metabolite of GTP, is produced by activated macrophages and is abundantly expressed within atherosclerotic lesions in human aorta and carotid and coronary arteries.
Remina Shirai, Kengo Sato, Tomoyuki Yamashita, Maho Yamaguchi, Taisuke Okano, Kaho Watanabe‐Kominato, Rena Watanabe, Taka‐aki Matsuyama, Hatsue Ishibashi‐Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu Hirano, Takuya Watanabe   +12 more
doaj   +1 more source

Urinary Neopterin Concentrations in Healthy Individuals with Household Contact

Pteridines, 2003
Increased neopterin concentrations in serum and urine indicate activation of cell-mediated immunity. In this study, urinary neopterin concentrations of a family consisting of 1 child (aged 5 years), her parents, and her grandparents were determined over ...
Winkler Christiana, Wirleitner Barbara, Werner Ernst R., Fuchs Dietmar   +3 more
doaj   +1 more source

The relationship between neopterin and hepatitis B surface antigen positivity

Pteridines, 2018
Hepatitis B is a life-threatening viral liver infection caused by the hepatitis B virus. Neopterin is regarded as an immunologic biomarker of several diseases related to activation of the cellular immune system.
Ünüvar Songül Ü, Aslanhan Hamza, Tanrıverdi Zübeyde, Karakuş Fuat   +3 more
doaj   +1 more source