Results 101 to 110 of about 25,310 (262)

Classification of Diabetic Retinopathy Images Using Multi-Class Multiple-Instance Learning Based on Color Correlogram Features [PDF]

arXiv, 2017
All people with diabetes have the risk of developing diabetic retinopathy (DR), a vision-threatening complication. Early detection and timely treatment can reduce the occurrence of blindness due to DR. Computer-aided diagnosis has the potential benefit of improving the accuracy and speed in DR detection.
arxiv  

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Corneal Lymphatics: Role in Ocular Inflammation as Inducer and Responder of Adaptive Immunity [PDF]

, 2015
The normal cornea is devoid of lymphatic and blood vessels, thus suppressing both the afferent (lymphatic) and efferent (vascular) arms of the immune response–contributing to its ‘immune privilege’. Inflammation, however, negates this unique ‘immune’ and
Chauhan, Sunil K., Dana, Reza, Dohlman, Thomas H.   +2 more
core   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Progress and Perspectives in 2D Piezoelectric Materials for Piezotronics and Piezo‐Phototronics

Advanced Science, EarlyView.
This review examines advancements in 2D materials, focusing on their applications in piezotronics and piezo‐phototronics. It discusses key materials like TMDs, h‐BN, and phosphorene, highlighting their unique mechanical, electronic, and optical properties.
Fengyi Pang, Pin Zhao, Hyeon Yeong Lee, Dae‐Jin Kim, Xiangchun Meng, Yong Soo Cho, Sang‐Woo Kim   +6 more
wiley   +1 more source

Dysfunctional stem and progenitor cells impair fracture healing with age [PDF]

, 2019
Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new vasculature that supplies ...
Clauss, Matthias, Fennimore, Alanna, Gunderson, Zachary J., Kacena, Melissa A., Karnik, Sonali, Li, Jiliang, Loghmani, M. Terry, Low, Philip S., Lowery, Jonathan W., McKinley, Todd O., Nielsen, Jeffery J., Promer, Hunter J., Wagner, Diane R.   +12 more
core   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

Platelet Lysate to Promote Angiogenic Cell Therapies [PDF]

, 2017
Cellular therapies for patients with ischemic muscle have been limited by poor cell retention and survivability. Platelets are a robust source of growth factors and structural proteins, and extracts from this peripheral blood component may be manipulated
Brewster, Luke P., Robinson, Scott T.
core   +2 more sources

Ultrasound‐Induced Nitric Oxide‐Propelled Nanomotor for Multimodal Theranostics of Cancer with Deep Penetration and Extended Lifetime

Advanced Science, EarlyView.
A hollow nanomotor (PM‐HMSN/Arg) propelled by ultrasound‐triggered nitric oxide (NO) was developed. The nanomotor employs a “tethering‐relaxing‐drilling” mechanism to overcome biological barriers, enabling multimodal theranostics of cancer with deep penetration and extended lifetime.
Xue Xu, Jinxu Cao, Yan Mu, Hao Zhang, Ya‐Lei Wang, Mengzhen Chen, Yuce Li, Qian Hua   +7 more
wiley   +1 more source

A Bio‐Responsive Hydrogel with Spatially Heterogeneous Structure for Treating Infectious Tissue Injuries

Advanced Science, EarlyView.
The hydrogel incorporates Ag⁺‐loaded Preyssler‐type polyoxometalates (POMs) that release Ag⁺ ions in response to endogenous Na⁺ ions, ensuring controlled antibacterial activity. The spatially heterogeneous structure, created through dual‐channel fiber stacking and in situ cross‐linking, enhances structural integrity and promotes tissue regeneration ...
Zongtai Li, Tao Yang, Xiaolei Li, Panchao Yin, Bo Yang, Dongying Li, Yan Wang, Wei Teng, Qianqian Yu, Weichang Li   +9 more
wiley   +1 more source