Results 181 to 190 of about 25,310 (262)

Mast cells in human choroid and their role in age-related macular degeneration (AMD). [PDF]

Clin Exp Med
Ribatti D, Dammacco R.
europepmc   +1 more source

Deceptive ostial coronary lesions: Lack of relationship between imaging and physiology [PDF]

, 2003
Bitar, Saad, Bleyer, Frank, Herrmann, Steven C., Kern, Morton J., Khoukaz, Souheil, Puri, Sanjeev, Ziaee, Ali   +6 more
core   +1 more source

Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap

Small Structures, EarlyView.
The constant fragment (Fc) of the immunoglobulin G1 (IgG1) subtype is a widely used scaffold for designing advanced therapeutics. Herein, together with the integration of experimental and computational techniques, this study reveals the structural dynamics of the N‐glycan‐bound Fc fragment of IgG1 from VEGF‐Trap, providing a new insight into enhancing ...
Ebru Destan, Engin Turkut, Alper Aldeniz, Jungmin Kang, Takehiko Tosha, Makina Yabashi, Baris Yilmaz, Ahmet Can Timucin, Hiroaki Matsuura, Yoshiaki Kawano, Irfan Cinkaya, Hasan DeMirci   +11 more
wiley   +1 more source

Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice. [PDF]

Biol Res
Guo Y, Qin J, Sun R, Hao P, Jiang Z, Wang Y, Gao Z, Zhang H, Xie K, Zhang W.   +9 more
europepmc   +1 more source

Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice [PDF]

, 2018
Akk, Antonina, Bacon, John, Hou, Kirk K, Miller, Mark J, Palekar, Rohun U, Pan, Hua, Pham, Christine T.N, Schlesinger, Paul H, Springer, Luke E, Wickline, Samuel A, Yan, Huimin, Yang, Lihua   +11 more
core   +1 more source

Right Once for All: Inflammation‐Targeted Zinc–Cobalt Metal–Organic Framework Nanozymes with High Stability and Broad‐Spectrum Synergistic Antibacterial Properties for Accelerating Bacteria‐Infected Wound Healing under Physiological Conditions

Small Structures, EarlyView.
Synergistic antibacterial nanoparticles (ZCMCC) composed of zinc‐cobalt metal‐organic frameworks (ZCM) loaded with chlorogenic acid (CGA) and modified with chitosan (CS) were developed. ZCMCC exhibited enhanced stability under physiological conditions, generated reactive oxygen species (ROS) via chemo‐dynamic therapy (CDT), and released CGA, achieving >
Xianchun Fu, Han Zhang, Zhi Liu, Li Yu, Yongtao Zhang, Changyao Wang   +5 more
wiley   +1 more source

Myofibroblast differentiation in a cat with eosinophilic sclerosing fibroplasia involving mesenteric lymph nodes and liver. [PDF]

J Vet Diagn Invest
Giannino DL, Jager MC, Brodlie H, Chien RC.   +3 more
europepmc   +1 more source

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Angiogenesis within atherosclerotic plaques: Mechanical regulation, molecular mechanism and clinical diagnosis. [PDF]

Mechanobiol Med
Chen H, Peng C, Fang F, Li Y, Liu X, Hu Y, Wang G, Liu X, Shen Y.   +8 more
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source