Results 51 to 60 of about 25,310 (262)
Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Brazilian Journal of Cardiovascular Surgery, 2008 OBJETIVO: As células progenitoras endoteliais (CPE), caracterizadas pelo marcador CD133+, contribuem para a neovascularização, e o aumento no número dessas células pode ser uma ferramenta terapêutica promissora. O sangue de cordão umbilical humano contém
Alexandra Cristina Senegaglia +7 more
doaj +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Analysis of Intra-Operative Physiological Responses Through Complex Higher-Order SVD for Long-Term Post-Operative Pain Prediction [PDF]
arXiv, 2021 Long-term pain conditions after surgery and patients' responses to pain relief medications are not yet fully understood. While recent studies developed an index for nociception level of patients under general anesthesia, based on multiple physiological parameters, it remains unclear whether and how dynamics of these parameters indicate long-term post ...
arxiv
Physiologically Driven Storytelling: Concept and Software Tool [PDF]
, 2020 We put forth Physiologically Driven Storytelling, a new approach to interactive storytelling where narratives adaptively unfold based on the reader's physiological state. We first describe a taxonomy framing how physiological signals can be used to drive interactive systems both as input and output.
arxiv +1 more source
Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. [PDF]
, 2019 PurposeMatrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases involved in wound healing processes, including neovascularization and fibrosis. We assessed MMP protein expression levels in diseased corneas of patients requiring
Chan, Matilda F +5 more
core
Advanced Biology, EarlyView.In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu +12 more
wiley +1 more source
Cells involved in extracellular matrix remodeling after acute myocardial infarction
Einstein (São Paulo)Objective Evaluate the effects of VEGF165 gene transfer in the process of remodeling of the extracellular matrix after an acute myocardial infarct. Methods Wistar rats were submitted to myocardial infarction, after the ligation of the left descending ...
Larissa Ferraz Garcia +5 more
doaj +1 more source
Veins and Lymphatics, 2014 Traditional surgical treatment of varicose disease requires an invasive procedure like high ligation of sapheno femoral junction (SFJ), resulting in high recurrence rates, especially in the long term. The aim of this prospective randomized study was to
Stefano Ricci
doaj +1 more source
Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]
, 2011 Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H. +2 more
core