Results 91 to 100 of about 100,831 (270)
Bone construction surgery: A case report using recombinant human platelet‐derived growth factor‐BB
Abstract Background The position and condition of bone largely sets the stage for functional and esthetic implant success. In bone construction surgery, creating a sustainable functional matrix is complex, but necessary, to enable long‐term mechanotransduction and maintenance of soft tissue support.
George A. Mandelaris, Bradley DeGroot
wiley +1 more source
Current Advances of Antibacterial Biomaterials for Bone Regeneration
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong+3 more
wiley +1 more source
Vascular co‐option and vasculogenic mimicry mediate resistance to antiangiogenic strategies
Abstract Background The concept that all the tumors need the formation of new vessels to grow inspired the hypothesis that inhibition of angiogenesis would have led to “cure” cancer. The expectancy that this type of therapy would have avoided the insurgence of resistance was based on the concept that targeting normal vessels, instead of the cancer ...
Francesco Pezzella, Domenico Ribatti
wiley +1 more source
Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui+5 more
wiley +1 more source
VEGF-mediated angiogenesis is a key mechanism of pathologic retinal neovascularization in the proliferative diabetic retinopathy (PDR). Therefore, the anti-VEGF therapy can be considered as a perspective approach for the treatment of this complication ...
V. I. Konenkov+3 more
doaj
Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana+5 more
wiley +1 more source
Editorial: New insight into the diagnosis and treatment of age-related macular degeneration
Andrea Servillo+5 more
doaj +1 more source
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
DISCOVER: 2-D Multiview Summarization of Optical Coherence Tomography Angiography for Automatic Diabetic Retinopathy Diagnosis [PDF]
Diabetic Retinopathy (DR), an ocular complication of diabetes, is a leading cause of blindness worldwide. Traditionally, DR is monitored using Color Fundus Photography (CFP), a widespread 2-D imaging modality. However, DR classifications based on CFP have poor predictive power, resulting in suboptimal DR management.
arxiv +1 more source
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu+7 more
wiley +1 more source