Results 11 to 20 of about 228,782 (391)

Neovascular Glaucoma [PDF]

Delhi Journal of Ophthalmology, 2015
Neovascular glaucoma (NVG) is a secondary ocular pathological condition resulting from a myriad of ocular and systemic conditions with retinal ischemia as a mediator in over 95% of cases. NVG is caused by the growth of a fibrovascular membrane secondary to a local angiogenic stimulus over the trabecular meshwork obstructing aqueous outflow.
Shane J, Havens, Vikas, Gulati
  +7 more sources

Neovascularization Detection and Localization in Fundus Images Using Deep Learning

Italian National Conference on Sensors, 2021
Proliferative Diabetic Retinopathy (PDR) is a severe retinal disease that threatens diabetic patients. It is characterized by neovascularization in the retina and the optic disk. PDR clinical features contain highly intense retinal neovascularization and
M. Tang, S. S. Teoh, H. Ibrahim, Zunaina Embong   +3 more
semanticscholar   +1 more source

Clinical and morphological aspects of the development of secondary ophthalmic hypertension in uveal melanoma

Российский офтальмологический журнал, 2022
Ophthalmic hypertension is mostly associated with medium- or large-sized melanomas. The pathogenesis of persistent IOP elevation in uveal melanoma is not fully understood at present.   Purpose.
E. E. Grishina, G. R. Setdikova, I. D. Kim, A. M. Bogatyrev, I. A. Loskutov, E. R. Eremeeva   +5 more
doaj   +1 more source

The G‐protein‐coupled chemoattractant receptor Fpr2 exacerbates neuroglial dysfunction and angiogenesis in diabetic retinopathy

FASEB BioAdvances, 2020
Diabetic retinopathy (DR) as a retinal neovascularization‐related disease is one of the leading causes of irreversible blindness in patients. The goal of this study is to determine the role of a G‐protein‐coupled chemoattractant receptor (GPCR) FPR2 ...
Ying Yu, Shengding Xue, Keqiang Chen, Yingying Le, Rongrong Zhu, Shiyi Wang, Shuang Liu, Xinliang Cheng, Huaijin Guan, Ji Ming Wang, Hui Chen   +10 more
doaj   +1 more source

Aminopeptidase N inhibition could be involved in the anti-angiogenic effect of dobesilates [PDF]

Journal of the Serbian Chemical Society, 2015
Calcium, magnesium and zinc 2,5-dihydroxybenzenesulfonates (dobesilates) were synthesized by sulfonation of hydroquinone with sulfuric acid under mild conditions.
Farsa Oldřich, Sedláková Šárka, Podlipná Jana, Maxa Jaroslav   +3 more
doaj   +1 more source

Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization

EMBO Molecular Medicine, 2023
Sphingosine‐1‐phosphate (S1P), the circulating HDL‐bound lipid mediator that acts via S1P receptors (S1PR), is required for normal vascular development. The role of this signaling axis in vascular retinopathies is unclear.
Colin Niaudet, Bongnam Jung, Andrew Kuo, Steven Swendeman, Edward Bull, Takahiro Seno, Reed Crocker, Zhongjie Fu, Lois E H Smith, Timothy Hla   +9 more
doaj   +1 more source

Filgrastim, fibrinolysis, and neovascularization [PDF]

Journal of Tissue Engineering and Regenerative Medicine, 2022
Segmental recanalization of chronically occluded arteries was observed in patients with chronic limb-threatening ischemia (CLTI) treated with Filgrastim, a granulocyte colony stimulating factor, every 72 h for up to a month, and an infra-geniculate programmed compression pump (PCP) for 3 h daily.
Darwin Eton, Guolin Zhou, Tong‐Chuan He, Amelia Bartholomew, Rachana Patil   +4 more
openaire   +2 more sources

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP, Amano, S, Ambati, J, D'Amore, PA, Gragoudas, ES, Hida, T, Ishida, S, Kaji, Y, Miller, JW, Ng, YS, Oguchi, Y, Ogura, Y, Shima, DT, Usui, T, Yamashiro, K   +14 more
core   +1 more source

Ocular neovascularization [PDF]

Journal of Molecular Medicine, 2006
Retinal and choroidal vascular diseases constitute the most common causes of moderate and severe vision loss in developed countries. They can be divided into retinal vascular diseases, in which there is leakage and/or neovascularization (NV) from retinal vessels, and subretinal NV, in which new vessels grow into the normally avascular outer retina and ...
openaire   +2 more sources

Dual-Acting Antiangiogenic Gene Therapy Reduces Inflammation and Regresses Neovascularization in Diabetic Mouse Retina

Molecular Therapy: Nucleic Acids, 2020
Intravitreal injections of anti-vascular endothelial growth factor drugs have become the gold standard treatment for diabetic retinopathy (DR). However, several patients are classified as non-responders or poor responders to treatment.
Rute S. Araújo, Diogo B. Bitoque, Gabriela A. Silva   +2 more
doaj   +1 more source