Results 11 to 20 of about 175,739 (194)

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP, Amano, S, Ambati, J, D'Amore, PA, Gragoudas, ES, Hida, T, Ishida, S, Kaji, Y, Miller, JW, Ng, YS, Oguchi, Y, Ogura, Y, Shima, DT, Usui, T, Yamashiro, K   +14 more
core   +1 more source

Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization

eLife, 2019
Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation.
Wenxin Ma, Sean M Silverman, Lian Zhao, Rafael Villasmil, Maria M Campos, Juan Amaral, Wai T Wong   +6 more
doaj   +1 more source

Ocular neovascularization [PDF]

Journal of Molecular Medicine, 2006
Retinal and choroidal vascular diseases constitute the most common causes of moderate and severe vision loss in developed countries. They can be divided into retinal vascular diseases, in which there is leakage and/or neovascularization (NV) from retinal vessels, and subretinal NV, in which new vessels grow into the normally avascular outer retina and ...
openaire   +2 more sources

Neovascular Glaucoma [PDF]

, 2015
Neovascular glaucoma (NVG) is a secondary ocular pathological condition resulting from a myriad of ocular and systemic conditions with retinal ischemia as a mediator in over 95% of cases. NVG is caused by the growth of a fibrovascular membrane secondary to a local angiogenic stimulus over the trabecular meshwork obstructing aqueous outflow.
Shane J, Havens, Vikas, Gulati
openaire   +2 more sources

Combined therapy with bevacizumab and photodynamic therapy for myopic choroidal neovascularization:A one-year follow-up controlled study [PDF]

International Journal of Ophthalmology, 2014
AIM: To evaluate the efficacy and safety of a combined treatment for myopic choroidal neovascularization (CNV) using photodynamic therapy (PDT) and intravitreal bevacizumab and to compare it with intravitreal bevacizumab monotherapy.METHODS: Thirty-four ...
Sandro Saviano, Rita Piermarocchi, Pia E. Leon, Alessandro Mangogna, Andrea Zanei, Fabiano Cavarzeran Sc, Daniele Tognetto   +6 more
doaj   +1 more source

Early markers of angiogenesis and ischemia during bowel conduit neovascularization [PDF]

, 2017
Background Bowel flaps are a good and reliable method to restore the continuity of the aerodigestive tract. Radiated fields, contaminated recipient sites, or depleted recipient vessels may increase the risk for ischemic injury after transfer.
Chen, Hung-chi, Chen, Pei-yu, Ciudad, Pedro, Li, Yun-fen, Lo Torto, Federico, Manrique, Oscar J., Nguyen, Doan-minh, Wong, Alex   +7 more
core   +1 more source

Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice

Physiological Reports, 2021
Skeletal muscle anatomy and physiology are sexually dimorphic but molecular underpinnings and muscle‐specificity are not well‐established. Variances in metabolic health, fitness level, sedentary behavior, genetics, and age make it difficult to discern ...
Juliana O’Reilly, Kikumi D. Ono‐Moore, Sree V. Chintapalli, Jennifer M. Rutkowsky, Todd Tolentino, K. C. Kent Lloyd, I. Mark Olfert, Sean H. Adams   +7 more
doaj   +1 more source

Neovascular glaucoma [PDF]

Progress in Retinal and Eye Research, 2007
Neovascular glaucoma (NVG) is a severely blinding, intractable disease. The objective of this review is to provide detailed information on its basic and clinical aspects, to enable us to manage it logically. Therefore, its causes, pathogenesis and pathology, methods of early diagnosis and management are discussed.
openaire   +2 more sources

Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]

, 2017
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria, Fawzi, Amani, Gill, Manjot, Ma, Jeffrey, Nesper, Peter, Skondra, Dimitra   +5 more
core   +3 more sources

The complex TIE between macrophages and angiogenesis [PDF]

, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M., Avraham‐Davidi I., Baer C., Bailey A. S., Barnett F. H., Bonnardel J., Chakarov S., Chen L., Coffelt S. B., Corliss B. A., Cursiefen C., Daly C., Davies L. C., Davies L. C., De Palma M., De Palma M., De Palma M., De Palma M., De Palma M., De Spiegelaere W., DeFalco T., Deshmane S. L., Detry B., Dimova I., Dimova I., Eklund L., Elamaa H., Eubank T. D., Fantin A., Ferrari G., Fukuhara S., Ganta V. C., Ganta V. C., García S., Gerri C., Grunewald M., Guo L., Gurevich D. B., Hamm A., Hazan A. D., He H., Hoeffel G., Itoh M., Jetten N., Kim M., Kochhan E., Korhonen E. A., Korpelainen E. I., Krishnasamy K., Kumar A. H., Leibovich S. J., Lim H. Y., Liu C., Lucas T., Master Z., Metharom P., Michaeli S., Moldovan N. I., Moore E. M., Mueller S. B., Murdoch C., Murray P. J., Patel A. S., Polverini P. J., Potente M., Pucci F., Saharinen P., Saharinen P., Schif‐Zuck S., Schmeisser A., Seaman S. A., Seok S. H., Spiller K. L., Venneri M. A., Vestweber D., Webster N. L., West M. E. D., Willenborg S., Yamamoto S., Zajac E., Zenker D., Zhang W.   +81 more
core   +2 more sources