Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia [PDF]
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Aicher, A+5 more
core +1 more source
Neovascularization in Human Atherosclerosis [PDF]
In the absence of disease, microvessels provide vessel wall nutrients to the tunica media, while the intima is fed by oxygen diffusion from the lumen. As disease evolves and the tunica intima thickens, oxygen diffusion is impaired, and microvessels become the major source for nutrients to the vessel wall.
K-Raman Purushothaman+4 more
openaire +5 more sources
Neovascularization is required in high-grade glioma (HGG). The objective of this study was to explore neovascularization-related genes and their corresponding MRI biomarkers during the early-growth stage of HGG.
Wei Xue+18 more
doaj +1 more source
Fluorescein angiography compared to three-dimensional measurements by the retinal thickness analyzer in classic choroidal neovascularization [PDF]
Purpose: To compare and correlate imaging of classic subfoveal choroidal neovascularization (CNV) with noninvasive 3-dimensional imaging by the retinal thickness analyzer (RTA) to conventional fluorescein angiography (FA).
Kampik, Anselm+3 more
core +1 more source
Endothelial progenitor cells and burn injury - exploring the relationship. [PDF]
Burn wounds result in varying degrees of soft tissue damage that are typically graded clinically. Recently a key participant in neovascularization, the endothelial progenitor cell, has been the subject of intense cardiovascular research to explore ...
Adnani, Blake O+4 more
core +2 more sources
Tumor Neovascularization and Developments in Therapeutics
Tumors undergo fast neovascularization to support the rapid proliferation of cancer cells. Vasculature in tumors, unlike that in wound healing, is immature and affects the tumor microenvironment, resulting in hypoxia, acidosis, glucose starvation, immune
Yuki Katayama+6 more
semanticscholar +1 more source
Cost effectiveness of treatments for wet age-related macular degeneration [PDF]
Age-related macular degeneration (AMD) is a leading cause of blindness in people aged >= 50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems.
Annemans, Lieven+4 more
core +1 more source
Neovascularization in Tissue Engineering [PDF]
A prerequisite for successful tissue engineering is adequate vascularization that would allow tissue engineering constructs to survive and grow. Angiogenic growth factors, alone and in combination, have been used to achieve this, and gene therapy has been used as a tool to enable sustained release of these angiogenic proteins.
Dominique Shum-Tim, Jennifer Chung
openaire +3 more sources
Influence of aflibercept on CNV type II
The application of angiogenesis blockers is a main method of therapy for a wet form of age-r elated macular degeneration (AMD).Purpose. To determine an effect of aflibercept on morphological parameters of the retina and functional indicators of the ...
R. R. Fayzrakhmanov+3 more
doaj +1 more source
Inhibition of retinopathy of prematurity in rat by intravitreal injection of sorafenib [PDF]
AIM:To investigate the effect of intravitreal injection administered sorafenib, a multikinase inhibitor, in a rat model of oxygen-induced retinopathy (OIR).METHODS:Seven-day-old Sprague-Dawley rats (n=144) were randomly assigned to six groups.
Li-Li Tian+7 more
doaj +1 more source