Results 41 to 50 of about 8,883 (209)
Kidney International Reports, 2018 Minimal change disease is a common cause of nephrotic syndrome. In general, patients with minimal change disease respond to corticosteroids and have excellent long-term renal survival. However, some patients have less favorable outcome.
Nina A. van de Lest +6 more
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Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis. [PDF]
PLoS ONE, 2011 The assembly of specific synaptic connections represents a prime example of cellular recognition. Members of the Ig superfamily are among the most ancient proteins represented in the genomes of both mammalian and invertebrate organisms, where they ...
Nicola Wanner +5 more
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Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus.
PLoS ONE, 2018 Nephrin (Nphs1) is an adhesion protein that is expressed at the podocyte intercellular junction in the glomerulus. Nphs1 mutations in humans or deletion in animal genetic models results in a developmental failure of foot process formation.
Rakesh Verma +8 more
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Factors Affecting Circulating mRNA for Nephrin [PDF]
Clinical Chemistry, 2005 Kidney disease affects more than 20 million individuals in the United States alone. Although the causes of kidney failure are diverse, the glomerular filtration barrier is often the target of injury. Identification of the type of disease is important for targeting therapy.
Emanuela, Orlandi +3 more
openaire +2 more sources
Nephrin-deleted mature podocyte fail to recover following protamine sulfate injury.
, 2018 (A) SEM images of kidneys from 8 weeks old Nphs1fl/fl,iCre(ER)T2 mice following protamine sulfate injury. Nphs1fl/fl,iCre(ER)T2 mice that received tamoxifen show failure of foot process recovery in response to heparin sulfate following injury with ...
Rakesh Verma (151646) +8 more
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Cells, 2022 Urolithins are bioactive compounds generated in human and animal intestines because of the bacterial metabolism of dietary ellagitannins (and their constituent, ellagic acid).
Milena Kotewicz +6 more
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Nephrin Expression Is Reduced in Human Diabetic Nephropathy
, 2003 We studied the distribution of nephrin in renal biopsies from 17 patients with diabetes and nephrotic syndrome (7 type 1 and 10 type 2 diabetes), 6 patients with diabetes and microalbuminuria (1 type 1 and 5 type 2 diabetes), and 10 normal subjects ...
Doublier, Sophie +13 more
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Nephrin phosphorylation regulates podocyte adhesion through the PINCH-1-ILK-α-parvin complex [PDF]
BMB Reports, 2013 Nephrin, a structural molecule, is also a signaling molecule afterphosphorylation. Inhibition of nephrin phosphorylation iscorrelated with podocyte injury.
Dongqing Zha +7 more
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Frontiers in Pharmacology, 2021 Modified Huangqi Chifeng decoction (MHCD) has been used to reduce proteinuria in immunoglobulin A nephropathy (IgAN) for many years. Previously, we have demonstrated its protective role in glomerular mesangial cells.
Meiying Chang +7 more
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, 2013 Western blot analysis of podocytes showing a down-regulation of nephrin with increasing concentrations (0-100 nM) of EVL and SRL after 48 h of incubation, respectively (A, B); expression of nephrin in the simultaneous analysis (20 nM) was lower in SRL ...
Lars P. Kihm (485769) +6 more
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