Results 11 to 20 of about 4,230,808 (299)

Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase [PDF]

open access: yesCommunications Biology, 2021
Amitai et al. identified 4 potential small molecule antidotes toward nerve agents poisoning by high-throughput-screening of over 150,000 compounds. Unique non-quaternary oximes represent new potential antidotes for future development as they detoxified ...
Gabriel Amitai   +10 more
doaj   +2 more sources

Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin [PDF]

open access: goldJournal of Neuroinflammation, 2011
Background Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well ...
Meyerhoff James L   +4 more
doaj   +2 more sources

Development of Nano Ache Enzyme Based Sensor for Determination of Nerve Agents Used in Chemical Weapons [PDF]

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2020
In this study; Nano enzyme system based sensor system has been developed for detection of nerve agents used in chemical weapons production. The chemical substances forming the nerve agents are included in the group of organophosphorus compounds. Paraoxon
Ozan YAĞMUROĞLU, Sibel Emir DİLTEMİZ
doaj   +1 more source

Environmentally Benign Biosynthesis of Hierarchical MOF/Bacterial Cellulose Composite Sponge for Nerve Agent Protection.

open access: yesAngewandte Chemie, 2022
The fabrication of MOF polymer composite materials enables the practical applications of MOF-based technology, in particular for protective suits and masks.
Yuk Ha Cheung   +9 more
semanticscholar   +1 more source

Leveraging Dissolution by Autoinjector Designs

open access: yesPharmaceutics, 2022
Chemical warfare or terrorism attacks with organophosphates may place intoxicated subjects under immediate life-threatening and psychologically demanding conditions.
Christoph Spangardt   +6 more
doaj   +1 more source

Thermocatalytic Decomposition of Dimethyl Methylphosphonate Based on CeO2 Catalysts with Different Morphologies

open access: yesApplied Sciences, 2023
The catalytic performances of the catalysts and decomposition mechanisms of dimethyl methylphosphonate (DMMP), a commonly used nerve agent simulant, are well understood based on previous studies.
Weimin Kong   +6 more
doaj   +1 more source

UiO-66-NH2 and Zeolite-Templated Carbon Composites for the Degradation and Adsorption of Nerve Agents

open access: yesMolecules, 2021
Composites of metal-organic frameworks and carbon materials have been suggested to be effective materials for the decomposition of chemical warfare agents.
Jaeheon Lee   +5 more
doaj   +1 more source

Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning [PDF]

open access: yesRoyal Society Open Science, 2019
Novichoks are the suspected nerve agents in the March 2018 Skripal poisoning. In this context, the novichok agent A234 (chemical structure proposed by Mirzayanov) was studied using computational methods to shed light on its molecular, electronic ...
Hanusha Bhakhoa   +2 more
doaj   +1 more source

Nerve agents: emergency preparedness [PDF]

open access: yesBMJ Military Health, 2020
Nerve agents (NAs) are a highly toxic group of chemical warfare agents. NAs are organophosphorus esters with varying physical and chemical properties depending on the individual agent. The most recently developed class of NA is‘Novichok’, the existence of which was first revealed in the early 1990s, just before Russia signed the Chemical Weapons ...
Alan George Andrew Weir   +2 more
openaire   +3 more sources

Nerve Agents and Their Detection [PDF]

open access: yesJournal of Sensor Science and Technology, 2014
Nerve agents are major chemical warfare agents with the “G series” and “V series” being the most widely known because of their lethal effect. Although not conspicuously used in major wars, the potential detrimental impact on modern society had been revealed from the sarin terror attack on Tokyo subway, which affected thousands of people.
Jae Doo Huh, Youngjun Kim
openaire   +2 more sources

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