Results 11 to 20 of about 3,812 (144)

Evaluation of Potency of Known Oximes (Pralidoxime, Trimedoxime, HI-6, Methoxime, Obidoxime) to in vitro Reactivate Acetylcholinesterase Inhibited by Pesticides (Chlorpyrifos and Methylchlorpyrifos and Nerve Agent (Russian VX) [PDF]

open access: diamondActa Medica, 2007
Nerve agents and pesticides belong to the group of organophosphates. They are able to inhibit irreversibly the enzyme acetylcholinesterase (AChE). Acetylcholinesterase reactivators were designed for the treatment of nerve agent intoxications.
Kamil Musílek, Kamil Kuča, Daniel Jun
doaj   +2 more sources

LABORATORY EXAMINATION IN NERVE AGENT INTOXICATION [PDF]

open access: yesActa Medica, 2013
Diagnosis of nerve agent intoxication is based on anamnestic data, clinical signs and laboratory examination. For acute poisoning, cholinesterase activity in the blood (erythrocyte AChE, plasma/serum BuChE) is sensitive, simple and most frequent ...
Jiří Bajgar
doaj   +4 more sources

Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin [PDF]

open access: goldJournal of Neuroinflammation, 2011
Background Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well ...
Meyerhoff James L   +4 more
doaj   +2 more sources

Development of Nano Ache Enzyme Based Sensor for Determination of Nerve Agents Used in Chemical Weapons [PDF]

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2020
In this study; Nano enzyme system based sensor system has been developed for detection of nerve agents used in chemical weapons production. The chemical substances forming the nerve agents are included in the group of organophosphorus compounds. Paraoxon
Ozan YAĞMUROĞLU, Sibel Emir DİLTEMİZ
doaj   +1 more source

Leveraging Dissolution by Autoinjector Designs

open access: yesPharmaceutics, 2022
Chemical warfare or terrorism attacks with organophosphates may place intoxicated subjects under immediate life-threatening and psychologically demanding conditions.
Christoph Spangardt   +6 more
doaj   +1 more source

Creating realistic nerve agent victim profiles for computer simulation of medical CBRN disaster response

open access: yesFrontiers in Public Health, 2023
In the last decades, Chemical, Biological, Radiological and Nuclear (CBRN) threats have become serious risks prompting countries to prioritize preparedness for such incidents.
Ruben De Rouck   +7 more
doaj   +1 more source

UiO-66-NH2 and Zeolite-Templated Carbon Composites for the Degradation and Adsorption of Nerve Agents

open access: yesMolecules, 2021
Composites of metal-organic frameworks and carbon materials have been suggested to be effective materials for the decomposition of chemical warfare agents.
Jaeheon Lee   +5 more
doaj   +1 more source

Thermocatalytic Decomposition of Dimethyl Methylphosphonate Based on CeO2 Catalysts with Different Morphologies

open access: yesApplied Sciences, 2023
The catalytic performances of the catalysts and decomposition mechanisms of dimethyl methylphosphonate (DMMP), a commonly used nerve agent simulant, are well understood based on previous studies.
Weimin Kong   +6 more
doaj   +1 more source

Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning [PDF]

open access: yesRoyal Society Open Science, 2019
Novichoks are the suspected nerve agents in the March 2018 Skripal poisoning. In this context, the novichok agent A234 (chemical structure proposed by Mirzayanov) was studied using computational methods to shed light on its molecular, electronic ...
Hanusha Bhakhoa   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy