Results 1 to 10 of about 4,225,584 (267)

Efficient Detection of Nerve Agents through Carbon Nitride Quantum Dots: A DFT Approach [PDF]

open access: yesNanomaterials, 2023
V-series nerve agents are very lethal to health and cause the inactivation of acetylcholinesterase which leads to neuromuscular paralysis and, finally, death. Therefore, rapid detection and elimination of V-series nerve agents are very important. Herein,
Yasair S. S. Al-Faiyz   +7 more
doaj   +3 more sources

Hydrolysis and enzymatic degradation of Novichok nerve agents [PDF]

open access: yesHeliyon, 2020
Several parameters of the Novichok nerve agents A230, A232 and A234 were determined. Hydrolysis rates were approximately one to three orders of magnitude slower than G-type nerve agents and approximately zero to two orders of magnitude slower than V-type
Steven P. Harvey   +2 more
doaj   +3 more sources

Enzymatic Decontamination of G-Type, V-Type and Novichok Nerve Agents. [PDF]

open access: yesInt J Mol Sci, 2021
Organophosphorus nerve agents (OPNAs) are highly toxic compounds inhibiting cholinergic enzymes in the central and autonomic nervous systems and neuromuscular junctions, causing severe intoxications in humans.
Jacquet P   +7 more
europepmc   +2 more sources

Molecular Recognition of Nerve Agents and Their Organophosphorus Surrogates: Toward Supramolecular Scavengers and Catalysts. [PDF]

open access: yesChemistry, 2021
Nerve agents are tetrahedral organophosphorus compounds (OPs) that were developed in the last century to irreversibly inhibit acetylcholinesterase (AChE) and therefore impede neurological signaling in living organisms.
Finnegan TJ   +2 more
europepmc   +2 more sources

Fluorescence umpolung enables light-up sensing of N-acetyltransferases and nerve agents. [PDF]

open access: yesNat Commun, 2021
Intramolecular charge transfer (ICT) is a fundamental mechanism that enables the development of numerous fluorophores and probes for bioimaging and sensing.
Yan C   +7 more
europepmc   +2 more sources

Organophosphorus Nerve Agents: Types, Toxicity, and Treatments. [PDF]

open access: yesJ Toxicol, 2020
Organophosphorus compounds are extensively used worldwide as pesticides which cause great hazards to human health. Nerve agents, a subcategory of the organophosphorus compounds, have been produced and used during wars, and they have also been used in ...
Mukherjee S, Gupta RD.
europepmc   +2 more sources

Counteracting poisoning with chemical warfare nerve agents. [PDF]

open access: yesArh Hig Rada Toksikol, 2020
Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of ...
Hrvat NM, Kovarik Z.
europepmc   +2 more sources

Catalytic Degradation of Nerve Agents [PDF]

open access: yesCatalysts, 2020
Nerve agents (NAs) are a group of highly toxic organophosphorus compounds developed before World War II. They are related to organophosphorus pesticides, although they have much higher human acute toxicity than commonly used pesticides.
Agatino Zammataro   +3 more
semanticscholar   +3 more sources

A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study [PDF]

open access: yesMolecules, 2021
Organophosphorous nerve agents (OPNA) pose an actual and major threat for both military and civilians alike, as an upsurge in their use has been observed in the recent years.
Janek Bzdrenga   +5 more
doaj   +2 more sources

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