Extraction and identification of lethal nerve agents and their markers in complex organic background have a prime importance from the forensic and verification viewpoint of the Chemical Weapons Convention (CWC). Liquid-liquid extraction with acetonitrile
Kanchan Sinha Roy+5 more
semanticscholar +1 more source
Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura+6 more
core +2 more sources
New derivatives of cyclodextrins were prepared in order to determine the relative importance of the structural key elements involved in the degradation of organophosphorus nerve agents.
Sophie Letort+6 more
doaj +1 more source
Fluorometric and Colorimetric Biosensors for the Assay of Cholinesterase Inhibitors
Cholinesterases, specifically acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), play critical roles in neurotransmission and are key targets for inhibitors with therapeutic and toxicological significance.
Miroslav Pohanka
doaj +1 more source
Investigating possibilities and recent trends for the development of novel decontamination technologies [PDF]
Despite international prohibition of chemical warfare agents (CWAs), defined in Chemical Weapons Convention, recent events during military conflict in Syria and isolated events in Salisbury (UK) and Kuala Lumpur (Malesya) airport prove that these agents ...
Vitorović-Todorović Maja D.+1 more
doaj +1 more source
Successful use of axonal transport for drug delivery by synthetic molecular vehicles [PDF]
We report the use of axonal transport to achieve intraneural drug delivery. We constructed a novel tripartite complex of an axonal transport facilitator conjugated to a linker molecule bearing up to a hundred reversibly attached drug molecules.
Aaron G. Filler+12 more
core +1 more source
Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow? [PDF]
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins.
Crawford, C.+4 more
core +2 more sources
In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase
The implementation of the Chemical Weapons Convention (CWC) in 1997 was a milestone in the prohibition of chemical warfare agents (CWA). Yet, the repeated use of CWA underlines the ongoing threat to the population.
Franz Worek+3 more
doaj +1 more source
Nerve-targeted probes for fluorescence-guided intraoperative imaging. [PDF]
A fundamental goal of many surgeries is nerve preservation, as inadvertent injury can lead to patient morbidity including numbness, pain, localized paralysis and incontinence.
Crisp, Jessica L+9 more
core
Advances in the diagnosis, immunopathogenesis and therapies of IgM-anti-MAG antibody-mediated neuropathies. [PDF]
Polyneuropathy with immunoglobulin M (IgM) monoclonal gammopathy is the most common paraproteinemic neuropathy, comprising a clinicopathologically and immunologically distinct entity.
Dalakas, Marinos
core +2 more sources