Theoretical prediction on the hydrolysis rate of the new types of nerve agents: A density functional study [PDF]
Toxicology Reports, 2023 Although the hydrolysis mechanism of the nerve agents, which is the main decontamination pathway, has been studied experimentally and theoretically, the reliable theoretical prediction method for the hydrolysis rate is not studied yet. Furthermore, after
Md Al Mamunur Rashid +3 more
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Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase [PDF]
Communications Biology, 2021 Amitai et al. identified 4 potential small molecule antidotes toward nerve agents poisoning by high-throughput-screening of over 150,000 compounds. Unique non-quaternary oximes represent new potential antidotes for future development as they detoxified ...
Gabriel Amitai +10 more
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Classification, Chemical, and Toxicological Properties of Carbamate Nerve Agents [PDF]
Journal of XenobioticsNerve agents are usually identified as exceedingly toxic organophosphate compounds like VX and sarin. Nevertheless, although carbamate nerve agents (CNAs) have been developed they constitute the least studied class of nerve agents outside military ...
Georgios Pampalakis
doaj +2 more sources
Chromogenic and fluorogenic reagents for chemical warfare nerve agents' detection [PDF]
, 2007 The ease of production, the extreme toxicity of organophosphorus-containing nerve agents, and their facile use in terrorism attacks underscores the need to develop accurate systems to detect these chemicals.
Santiago Royo +5 more
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Acute and long-term consequences of exposure to organophosphate nerve agents in humans. [PDF]
Epilepsia, 2018 Nerve agents are organophosphate (OP) compounds and among the most powerful poisons known to man. A terrorist attack on civilian or military populations causing mass casualties is a real threat. The OP nerve agents include soman, sarin, cyclosarin, tabun,
Figueiredo TH +3 more
europepmc +2 more sources
Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. [PDF]
J Pharmacol Exp Ther, 2018 Organophosphates (OP) such as the pesticide diisopropylfluorophosphate (DFP) and the nerve agent sarin are lethal chemicals that induce seizures, status epilepticus (SE), and brain damage.
Wu X, Kuruba R, Reddy DS.
europepmc +2 more sources
Toxic chemical weapons of assassination and warfare: nerve agents VX and sarin. [PDF]
Toxicol Commun, 2017 The use of VX and sarin as weapons of assassination and warfare raises important considerations for healthcare professionals who may encounter victims, bystanders, and responders who require prompt assessment and treatment.
Chai PR +3 more
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3D Fractals as SERS Active Platforms: Preparation and Evaluation for Gas Phase Detection of G-Nerve Agents [PDF]
Micromachines, 2018 One of the main limitations of the technique surface-enhanced Raman scattering (SERS) for chemical detection relies on the homogeneity, reproducibility and reusability of the substrates.
Marta Lafuente +5 more
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Detoxification of VX and Other V-Type Nerve Agents in Water at 37 °C and pH 7.4 by Substituted Sulfonatocalix[4]arenes. [PDF]
Angew Chem Int Ed Engl, 2016 Sulfonatocalix[4]arenes with an appended hydroxamic acid residue can detoxify VX and related V‐type neurotoxic organophosphonates with half‐lives down to 3 min in aqueous buffer at 37 °C and pH 7.4.
Schneider C +4 more
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After Salisbury Nerve Agents Revisited
Molecular Informatics, 2018 In March 2018 the term Novichok (Hoвичoκ) became publically known following an attempted murder of a former Russian spy in Salisbury, UK. Novichok is the name of a group of nerve agents secretly produced by Russia in the later stages of the Cold War ...
L. Carlsen
semanticscholar +3 more sources