Results 11 to 20 of about 431,436 (299)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa +14 more
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Nerve agents: emergency preparedness [PDF]
BMJ Military Health, 2020 Nerve agents (NAs) are a highly toxic group of chemical warfare agents. NAs are organophosphorus esters with varying physical and chemical properties depending on the individual agent. The most recently developed class of NA is‘Novichok’, the existence of which was first revealed in the early 1990s, just before Russia signed the Chemical Weapons ...
Alan George Andrew Weir +2 more
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Journal of Pharmacy and Bioallied Sciences, 2010 Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare.
K Ganesan, S K Raza, R Vijayaraghavan
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Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition
Toxics, 2023 Organophosphorus compounds (OPs) have applications in agriculture (e.g., pesticides), industry (e.g., flame retardants), and chemical warfare (nerve agents). In high doses or chronic exposure, they can be toxic or lethal.
Vassiliki Aroniadou-Anderjaska +4 more
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Applied Sciences, 2021 The smart, rapid, and customizable detection of chemical warfare agents is a huge issue for taking the proper countermeasures in a timely fashion. The printing techniques have established the main pillar to develop miniaturized electrochemical biosensors
Fabiana Arduini
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Sensors, 2015 Organophosphates are organic substances that contain a phosphoryl or a thiophosphoryl bond. They are mainly used around the world as pesticides, but can also be used as chemical warfare agents. Their detection is normally entrusted to techniques like GC-
Paola Carullo +4 more
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Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model [PDF]
, 2011 The purpose of this study is to develop a rodent functional magnetic resonance imaging (fMRI) survival model with the use of heparin-coated vascular access devices.
Cho, Younghoon R +7 more
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Acetylcholinesterase: The “Hub” for Neurodegenerative Diseases and Chemical Weapons Convention
Biomolecules, 2020 This article describes acetylcholinesterase (AChE), an enzyme involved in parasympathetic neurotransmission, its activity, and how its inhibition can be pharmacologically useful for treating dementia, caused by Alzheimer’s disease, or as a warfare ...
Samir F. de A. Cavalcante +7 more
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, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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Chromogenic and fluorogenic reagents for chemical warfare nerve agents' detection [PDF]
, 2007 The ease of production, the extreme toxicity of organophosphorus-containing nerve agents, and their facile use in terrorism attacks underscores the need to develop accurate systems to detect these chemicals.
Ana M. Costero +42 more
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