Results 21 to 30 of about 4,225,584 (267)

A clinical approach to an unidentified aerosolized bioterrorism agent: a narrative review for emergency providers [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2023
The current heightened international political climate is accompanied by increased risk of chemical or biological agent weaponization. Historical accounts of biochemical warfare are extensive, and considering the recent use of such agents for targeted ...
Rashed Alremeithi   +4 more
doaj   +1 more source

NERVE AGENTS OF NERVE ACTION

open access: yesMilitary Medicine, 2023
Observations of military conflicts and local wars of recent decades show us that the concept of "chemical weapons" has not yet been deleted from the military lexicon of various countries, despite the convention on its prohibition.
Bova A. A.   +5 more
semanticscholar   +1 more source

Detection of a Nerve Agent Simulant by a Fluorescent Sensor Array

open access: yesChemosensors, 2023
Detection of nerve agents (NAs) gas in the environment through portable devices to protect people in case of emergencies still remains a challenge for scientists involved in this research field. Current detection strategies require the use of cumbersome,
Rossella Santonocito   +5 more
doaj   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa   +14 more
doaj   +1 more source

Nerve agents: emergency preparedness [PDF]

open access: yesBMJ Military Health, 2020
Nerve agents (NAs) are a highly toxic group of chemical warfare agents. NAs are organophosphorus esters with varying physical and chemical properties depending on the individual agent. The most recently developed class of NA is‘Novichok’, the existence of which was first revealed in the early 1990s, just before Russia signed the Chemical Weapons ...
Alan George Andrew Weir   +2 more
openaire   +3 more sources

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

open access: yes, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert   +15 more
core   +11 more sources

Nerve Agents and Their Detection [PDF]

open access: yesJournal of Sensor Science and Technology, 2014
Nerve agents are major chemical warfare agents with the “G series” and “V series” being the most widely known because of their lethal effect. Although not conspicuously used in major wars, the potential detrimental impact on modern society had been revealed from the sarin terror attack on Tokyo subway, which affected thousands of people.
Jae Doo Huh, Youngjun Kim
openaire   +2 more sources

Chemical warfare agents

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare.
K Ganesan, S K Raza, R Vijayaraghavan
doaj   +3 more sources

Characterization of the Interaction of Nerve Agent Mimics with Selected Synthetic Receptors

open access: yesOrganic Materials, 2022
Qualitative NMR spectroscopic and quantitative calorimetric binding studies were performed to characterize the interaction of nontoxic mimics of the V-type nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) and the Novichok ...
Carolina Braga Barbosa   +3 more
doaj   +1 more source

Continuous Opioid Monitoring along with Nerve Agents on a Wearable Microneedle Sensor Array.

open access: yesJournal of the American Chemical Society, 2020
There are urgent needs for sensing devices capable of distin-guishing between episodes of opioid overdose and nerve agent poisoning. This work presents a wearable microneedle sensor array for minimally-invasive continuous electrochemical detection of ...
R. Mishra   +7 more
semanticscholar   +1 more source

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