Results 31 to 40 of about 205,418 (209)

Chemical warfare agents: Structure, properties, decontamination (part 1)

Журнал органічної та фармацевтичної хімії
The review is aimed at summarizing and systematizing information on various methods of deactivation of chemical warfare agents required on the battlefield, in laboratories, research institutions, production facilities, as well as information on storage ...
Alexander E. Shumeiko, Nikolai I. Korotkikh   +1 more
doaj   +1 more source

STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION

Química Nova
Straightforward, microscale, Ellman's cholinesterase test procedures are presented, useful for screening of novel compounds aiming at neurodegenerative diseases and antidotes towards nerve agents and pesticides.
Samir F. de A. Cavalcante, Daniel A. S. Kitagawa, Rafael B. Rodrigues, Monique Cardozo, Reuel L. de Paula, Ana Beatriz de A. Correa, Alessandro B. C. Simas   +6 more
doaj   +1 more source

Variation of Cholinesterase-Based Biosensor Sensitivity to Inhibition by Organophosphate Due To Ionizing Radiation

Sensors, 2009
A cholinesterase based biosensor was constructed in order to assess the effects of ionizing radiation on exposed AChE. Although the primary objective of the experiment was to investigate the effect of ionizing radiation on the activity of the biosensor ...
Miroslav Pohanka, Miroslav Koch
doaj   +1 more source

Interactions of cyclodextrins and their derivatives with toxic organophosphorus compounds

Beilstein Journal of Organic Chemistry, 2016
The aim of this review is to provide an update on the current use of cyclodextrins against organophosphorus compound intoxications. Organophosphorus pesticides and nerve agents play a determinant role in the inhibition of cholinesterases.
Sophie Letort, Sébastien Balieu, William Erb, Géraldine Gouhier, François Estour   +4 more
doaj   +1 more source

Chemical Weapons: History of the Study of Organophosphorus Toxic Agents Abroad

Вестник войск РХБ защиты, 2023
Organophosphorus compounds occupy a unique positon among all chemical warfare agents (CWA's). Since the 1930-s their high toxicity, wide range of physical-chemical properties and complex action attracted close attention of foreign military experts.
I. A. Nelga, I. V. Medvetsky, A. V. Zlobin, S. V. Tretyakov, A. V. Sherstyuk, I. V. Kostyuchenko   +5 more
doaj   +1 more source

Complex View on Poisoning with Nerve Agents and Organophosphates

Acta Medica, 2005
OP/nerve agents are still considered as important chemicals acting on living organisms and widely used in human practice. Nerve agents are the most lethal chemical warfare agents.
Jiří Bajgar
doaj   +1 more source

Phenobarbital as alternate anticonvulsant for organophosphate‐induced benzodiazepine‐refractory status epilepticus and neuronal injury

Epilepsia Open, 2020
Objective Organophosphates (OPs) such as diisopropylfluorophosphate (DFP) and soman are lethal chemical agents that can produce seizures, refractory status epilepticus (SE), and brain damage.
Doodipala Samba Reddy, Dheepthi Perumal, Victoria Golub, Andy Habib, Ramkumar Kuruba, Xin Wu   +5 more
doaj   +1 more source

Acetylcholinesterase: The “Hub” for Neurodegenerative Diseases and Chemical Weapons Convention

Biomolecules, 2020
This article describes acetylcholinesterase (AChE), an enzyme involved in parasympathetic neurotransmission, its activity, and how its inhibition can be pharmacologically useful for treating dementia, caused by Alzheimer’s disease, or as a warfare ...
Samir F. de A. Cavalcante, Alessandro B. C. Simas, Marcos C. Barcellos, Victor G. M. de Oliveira, Roberto B. Sousa, Paulo A. de M. Cabral, Kamil Kuča, Tanos C. C. França   +7 more
doaj   +1 more source

Exploiting macrocyclic polylactam for sensing V-series nerve agents: A computational study

Results in Chemistry
The nerve agents are organophosphorus compounds (OPs) developed as chemical warfare agents (CWAs) that inhibit acetylcholinesterase (AChE) and lead to impeding neurological signals in mammals.
Dipankar Das, Bishwajit Ganguly
doaj   +1 more source

Assessing the Clinical Features and Blood Biochemistries of Acute Organophosphorus Chemical Warfare Agents in Iranian Veterans

International Journal of Medical Toxicology and Forensic Medicine, 2021
Background: Nerve Agents (NAs) are a chemical weapons, and their use is prohibited. They were used for numerous-times in the warfare of Iraq against Iran.
khosrow Agin , Babak Mostafazadeh
doaj   +1 more source