Results 11 to 20 of about 1,223,403 (400)

Correlated disorder in myelinated axons orientational geometry and structure [PDF]

open access: yesCondens. Matter 2(3), 29 (2017), 2017
While the ultrastructure of the myelin has been considered to be a quasi-crystalline stable system, nowadays its multiscale complex dynamics appears to play a key role for its functionality, degeneration and repair processes following neurological ...
Bianconi, Antonio   +3 more
core   +2 more sources

Retinal and optic nerve degeneration in α-mannosidosis. [PDF]

open access: yesOrphanet J Rare Dis, 2018
Backgroundα-mannosidosis is a rare, autosomal-recessive, lysosomal storage disease caused by a deficient activity of α-mannosidase. Typical symptoms include intellectual, motor and hearing impairment, facial coarsening, and musculoskeletal abnormalities.
Matlach J   +5 more
europepmc   +2 more sources

Baculoviral inhibitor of apoptosis protein repeat-containing protein 3 delays early Wallerian degeneration after sciatic nerve injury

open access: goldNeural Regeneration Research, 2022
Wallerian degeneration is a complex biological process that occurs after nerve injury, and involves nerve degeneration and regeneration. Schwann cells play a crucial role in the cellular and molecular events of Wallerian degeneration of the peripheral ...
Min Cai   +8 more
doaj   +2 more sources

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. [PDF]

open access: yesNat Med, 2018
Aging of hematopoietic stem cells (HSCs) is associated with a decline in their regenerative capacity and multilineage differentiation potential, contributing to the development of blood disorders.
Maryanovich M   +11 more
europepmc   +2 more sources

Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury

open access: goldNeural Regeneration Research, 2022
Wallerian degeneration, the progressive disintegration of distal axons and myelin that occurs after peripheral nerve injury, is essential for creating a permissive microenvironment for nerve regeneration, and involves cytoskeletal reconstruction. However,
Jingmin Liu   +16 more
doaj   +2 more sources

Pathology of Nerve Terminal Degeneration in the Skin [PDF]

open access: bronzeJournal of Neuropathology & Experimental Neurology, 2000
To characterize the pathology of epidermal nerve degeneration and regeneration, we investigated temporal and spatial changes in skin innervation of the mouse footpad. Within 24 hours after sciatic nerve axotomy, terminals of epidermal nerves appeared swollen and there was a mild reduction in epidermal nerve density (5.7 +/- 2.8 vs 12.7 +/- 2.2 fibers ...
Sung‐Tsang Hsieh   +2 more
openalex   +4 more sources

Selective Fiber Degeneration in the Peripheral Nerve of a Patient With Severe Complex Regional Pain Syndrome [PDF]

open access: goldFrontiers in Neuroscience, 2018
Aims: Complex regional pain syndrome (CRPS) is characterized by chronic debilitating pain disproportional to the inciting event and accompanied by motor, sensory, and autonomic disturbances. The pathophysiology of CRPS remains elusive.
Adrien Yvon   +5 more
doaj   +2 more sources

Effect of Spp1 on nerve degeneration and regeneration after rat sciatic nerve injury. [PDF]

open access: yesBMC Neurosci, 2017
BackgroundWallerian degeneration (WD) in injured peripheral nerves is associated with a large number of up- or down-regulated genes, but the effects of these changes are poorly understood.
Liu X   +7 more
europepmc   +2 more sources

Nerve degeneration and regeneration in the cephalopod mollusc Octopus vulgaris: the case of the pallial nerve. [PDF]

open access: yesSci Rep, 2017
Regeneration is a process that restores structure and function of tissues damaged by injury or disease. In mammals complete regeneration is often unsuccessful, while most of the low phyla animals can re-grow many parts of their body after amputation ...
Imperadore P   +3 more
europepmc   +2 more sources

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