Results 51 to 60 of about 1,249,880 (378)

Optical coherence tomography in Alzheimer's disease. A meta-analysis [PDF]

, 2015
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder, which is likely to start as mild cognitive impairment (MCI) several years before the its full-blown clinical manifestation.
Barboni, Piero, Coppola, Gianluca, Di Renzo, Antonio, Fadda, Antonello, Manni, Gianluca, Martelli, Francesco, Parisi, Vincenzo, Pierelli, Francesco, Sadun, Alfredo A., Ziccardi, Lucia   +9 more
core   +4 more sources

Axonal Protection by Ripasudil, a Rho Kinase Inhibitor, via Modulating Autophagy in TNF-Induced Optic Nerve Degeneration.

Investigative Ophthalmology and Visual Science, 2017
Purpose The Rho kinase inhibitor ripasudil decreases intraocular pressure, although its role in optic nerve axonal damage should be clarified. We therefore investigated whether ripasudil modulates TNF-induced axonal loss and affects autophagy machinery ...
Y. Kitaoka, Kana Sase, Chihiro Tsukahara, Kaori Kojima, Akira Shiono, Jiro Kogo, Naoto Tokuda, H. Takagi   +7 more
semanticscholar   +1 more source

Sciatic nerve injury following analgesic drug injection in rats: A histopathological examination

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]Sciatic nerve neuropathy can be observed following intramuscular gluteal injections. The histopathological examination of sciatic nerve damage following intramuscular injection in the gluteal region for acute pain treatment is not feasible
Habib Bostan, Murat Çabalar, Serdar Altınay, Yıldıray Kalkan, Levent Tumkaya, Ayhan Kanat, Sabri Balık, Adem Erkut, Dudu Altuner, Ziya Salihoğlu, Abdulkadir Koçer   +10 more
doaj   +1 more source

Preganglionic innervation of the pancreas islet cells in the rat [PDF]

, 1984
The position and number of preganglionic somata innervating the insulin-secreting β-cells of the endocrine pancreas were investigated in Wistar rats.
Horst, G.J. ter,, Koopmans, S.J.,, Luiten, P.G.M.,, Rietberg, M.,, Steffens, A.B.,   +4 more
core   +2 more sources

Fas Ligand Gene (Faslg) Plays an Important Role in Nerve Degeneration and Regeneration After Rat Sciatic Nerve Injury

Frontiers in Molecular Neuroscience, 2018
Wallerian degeneration (WD) is associated with changes in the expression levels of a large number of genes. However, the effects of these up- or down-regulated genes are poorly understood.
Yuting Li, Yuhua Sun, Min Cai, Huanhuan Zhang, Nannan Gao, Huiwei Huang, Shusen Cui, D. Yao   +7 more
semanticscholar   +1 more source

Correlated disorder in myelinated axons orientational geometry and structure

, 2017
While the ultrastructure of the myelin has been considered to be a quasi-crystalline stable system, nowadays its multiscale complex dynamics appears to play a key role for its functionality, degeneration and repair processes following neurological ...
Bianconi, Antonio, Campi, Gaetano, Di Gioacchino, Michael, Poccia, Nicola   +3 more
core   +1 more source

Enhanced sciatic nerve regeneration by relieving iron-overloading and organelle stress with the nanofibrous P(MMD-co-LA)/DFO conduits

Materials Today Bio, 2022
Wallerian degeneration after peripheral nerve injury (PNI), that is, the autonomous degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces oxidative stress caused by iron overload.
Lei Han, Xianzhen Dong, Tong Qiu, Zhaona Dou, Lin Wu, Honglian Dai   +5 more
doaj   +1 more source

Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. [PDF]

, 2018
Glaucoma is characterized by a progressive loss of retinal ganglion cells and their axons, but the underlying biological basis for the accompanying neurodegeneration is not known.
Bu, Jung Hyun, Ellisman, Mark H, Jeong, Seung Won, Ju, Won-Kyu, Kim, Keun-Young, Nam, Hye Seung, Park, Tae Lim, Shim, Myoung Sup, Weinreb, Robert N   +8 more
core   +2 more sources

CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice

Cell Death and Disease, 2021
Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by progressive optic nerve degeneration and retinal ganglion cell loss.
Meng Ye, Jingqiu Huang, Qianxue Mou, Jing Luo, Yuanyuan Hu, Xiaotong Lou, Ke Yao, Bowen Zhao, Qiming Duan, Xing Li, Hong Zhang, Yin Zhao   +11 more
doaj   +1 more source

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio, Reilly, James, Shu, Xinhua, Tiano, Luca, Tohari, Ali Mohammad, Zhang, Xun, Zhou, Xinzhi   +6 more
core   +1 more source