Results 21 to 30 of about 8,751,976 (243)

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects

Neural Regeneration Research, 2023
Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin, Hang Li, Jun-Ze Chen, Kai-Rui Zhang, Xing-Qi Zhao, Jian-Qiang Qin, Bin Yu, Jun Yang   +7 more
doaj   +1 more source

Nerve growth factors.

Nihon Naika Gakkai Zasshi, 1992
神経成長因子(nerve growth factor; NGF)は,知覚神経二ューロン,交感神経ニューロン,中枢の一部のコリン系ニューロンの分化・成熟を促し,生存・機能を維持し,突起伸展を引き起こす,分子量約26000の蛋白質である. NGFは,神経科学,発生学の分野において最も古くから実体の明らかにされていた分子のひとつで, NGFの研究で得られた膨大な知見から神経回路の形成過程や調節機構の概要が窺い知ることができるようになった.最近では, NGFを投与すると,末梢神経の軸索再生が促進されること,遅発性ニューロン死が抑制されること,老化による学習記憶能力低下が抑制されること,などが報告され,臨床応用への期待も高まってきている.
Y, Furukawa, S, Furukawa
openaire   +3 more sources

Biological characteristics of dynamic expression of nerve regeneration related growth factors in dorsal root ganglia after peripheral nerve injury

Neural Regeneration Research, 2020
The regenerative capacity of peripheral nerves is limited after nerve injury. A number of growth factors modulate many cellular behaviors, such as proliferation and migration, and may contribute to nerve repair and regeneration.
Yin-Ying Shen, Xiao-Kun Gu, Rui-Rui Zhang, Tian-Mei Qian, Shi-Ying Li, Sheng Yi   +5 more
doaj   +1 more source

Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]

, 2013
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M., Susan C Barnett, Gunn-Moore Frank J., Tilston-Lunel, Andrew Martin, Moleirinho, S., Jennifer R Higginson, Angus Liselotte, Prystowsky Michael B., Calum Patrick, Liselotte Angus, Andrew M. Tilston-lünel, Michael B. Prystowsky, Patrick, C., Susana Moleirinho, Frank J Gunn-Moore, Moleirinho Susana, Gunn-Moore, Frank J, Gunn-Moore, F.J., Prystowsky, M.B., Moleirinho, Susan, Paul A. Reynolds, Maciej Antkowiak, Susan C. Barnett, Jennifer R. Higginson, Antkowiak Maciej, Barnett Susan C., Paul A Reynolds, Higginson, J.R., Reynolds Paul A., Antkowiak, Maciej, Prystowsky, Michael, Michael B Prystowsky, Barnett, Susan, Antkowiak, M., Reynolds, Paul Andrew, Tilston-Lünel Andrew M., Barnett, S.C., Frank J. Gunn-moore, Angus, Liselotte, Andrew M Tilston-Lünel, Patrick Calum, Patrick, Calum, Higginson Jennifer R., Higginson, JR, Angus, L., Reynolds, P.A.   +45 more
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Mechanisms of nerve growth factor signaling in bone nociceptors and in an animal model of inflammatory bone pain

Molecular Pain, 2017
Sequestration of nerve growth factor has been used successfully in the management of pain in animal models of bone disease and in human osteoarthritis.
Sara Nencini, Mitchell Ringuet, Dong-Hyun Kim, Yu-Jen Chen, Claire Greenhill, Jason J Ivanusic   +5 more
doaj   +1 more source

Dynamics of expression rates of growth factor proteins in psoriatic patients receiving a phototherapy

Vestnik Dermatologii i Venerologii, 2017
Goal. To study the dynamics of expression rates of growth factor proteins in psoriatic patients receiving the PUVA therapy. Materials and methods. The authors conducted a study of 30 patients with psoriasis vulgaris treated with the PUVA therapy.
V. V. Chikin, M. B. Zhilova, V. A. Smolyannikova, M. A. Nefedova   +3 more
doaj   +1 more source

CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation

Frontiers in Molecular Neuroscience, 2021
Nerve growth factor (NGF) stimulates numerous cellular physiological processes, including growth, differentiation, and survival, and maintains the phenotype of several neuronal types.
Luciana Sampieri, Luciana Sampieri, Macarena Funes Chabán, Macarena Funes Chabán, Pablo Di Giusto, Pablo Di Giusto, Victoria Rozés-Salvador, Cecilia Alvarez, Cecilia Alvarez   +8 more
doaj   +1 more source

Eosinophil-mediated cholinergic nerve remodeling [PDF]

, 2006
Eosinophils are observed to localize to cholinergic nerves in a variety of inflammatory conditions such as asthma, rhinitis, eosinophilic gastroenteritis, and inflammatory bowel disease, where they are also responsible for the induction of cell ...
McLean, W.G., Anthony G. Fenech, Madziar, B., Madziar, Beata, Durcan, Niamh, Gleich, G.J., Walsh, M., Fenech, Anthony G., McLean, Graham W., Jan Blusztajn, Gerard J. Gleich, Gleich, Gerard J., Niamh Durcan, Hall, Ian P., Beata Madziar, Walsh, Marie-Therese, Hall, I.P., Ian P. Hall, Durcan, N., Costello, Richard W., Richard W. Costello, Marie-Therese Walsh, McGarvey, Lorcan, Costello, R.W., Fenech, A.G., W. Graham McLean, Lorcan McGarvey, Blusztain, J., Blusztajn, Jan   +28 more
core   +1 more source

Inflammation and itching in patients suffering from atopic dermatitis and psoriasis. Assessment of the expression of neurotrophins аnd neuropeptides

Vestnik Dermatologii i Venerologii, 2017
Goal. To assess the expression of neurotrophin, a nerve growth factor, amphiregulin, an epidermal growth factor, semaphorin 3A, a nerve repulsion factor, and PGP9.5 protein, a nerve fiber marker, in the skin of patients suffering from atopic dermatitis ...
V. A. Smolyannikova, A. A. Kubanova, V. V. Chikin, A. E. Karamova   +3 more
doaj   +1 more source

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

Neural Regeneration Research, 2020
Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro, Alessia Giovannelli, Angelica Foggetti, Luisa Muratori, Stefano Geuna, Giorgia Novajra, Isabelle Perroteau   +6 more
doaj   +1 more source