Results 31 to 40 of about 656,858 (381)

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects

open access: yesNeural Regeneration Research, 2023
Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin   +7 more
doaj   +1 more source

Development of affinity-based delivery of NGF from a chondroitin sulfate biomaterial. [PDF]

open access: yes, 2011
Chondroitin sulfate is a major component of the extracellular matrix in both the central and peripheral nervous systems. Chondroitin sulfate is upregulated at injury, thus methods to promote neurite extension through chondroitin sulfate-rich matrices and
Butterfield, Karen Chao   +2 more
core   +1 more source

Graphene promotes axon elongation through local stall of Nerve Growth Factor signaling endosomes [PDF]

open access: yes, 2020
Several works reported increased differentiation of neuronal cells grown on graphene; however, the molecular mechanism driving axon elongation on this material has remained elusive. Here, we study the axonal transport of nerve growth factor (NGF), the neurotrophin supporting development of peripheral neurons, as a key player in the time course of ...
arxiv   +1 more source

Nerve growth factor binding domain of the nerve growth factor receptor. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1991
A structural analysis of the rat low-affinity nerve growth factor (NGF) receptor was undertaken to define the NGF binding domain. Mutant NGF receptor DNA constructs were expressed in mouse fibroblasts or COS cells, and the ability of the mutant receptor to bind NGF was assayed.
Catherine M. Bitler   +3 more
openaire   +3 more sources

Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView., 2023
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal   +5 more
wiley   +1 more source

Unaltered low nerve growth factor and high brain-derived neurotrophic factor levels in plasma from patients with fibromyalgia after a 15-week progressive resistance exercise

open access: yesJournal of Rehabilitation Medicine, 2019
Background: The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and ...
Anna Jablochkova   +6 more
doaj   +1 more source

Nerve growth factor: basic findings and clinical trials [PDF]

open access: yes, 1999
The nerve growth factor is the first-discovered and best-characterized member of the family of neurotrophins. In the introduction of this article we present a brief biographic view of past and present studies of Rita Levi-Montalcini on nerve growth ...
Aloe, Luigi, Micera, Alessandra
core   +2 more sources

Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons [PDF]

open access: yes, 1989
Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the ...
Barde, Y. A.   +5 more
core   +2 more sources

Dynamics of expression rates of growth factor proteins in psoriatic patients receiving a phototherapy

open access: yesVestnik Dermatologii i Venerologii, 2017
Goal. To study the dynamics of expression rates of growth factor proteins in psoriatic patients receiving the PUVA therapy. Materials and methods. The authors conducted a study of 30 patients with psoriasis vulgaris treated with the PUVA therapy.
V. V. Chikin   +3 more
doaj   +1 more source

Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth [PDF]

open access: yesActa Biomaterialia 8, 9 (2012) 3302-3312, 2012
Designing synthetic microenvironments for cellular investigations is a very active area of research at the crossroads of cell biology and materials science. The present work describes the design and functionalization of a three-dimensional (3D) culture support dedicated to the study of neurite outgrowth from neural cells.
arxiv   +1 more source

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