Results 31 to 40 of about 1,892,908 (403)

Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons [PDF]

, 1989
Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the ...
Barde, Y. A., Borasio, Gian Domenico, Heumann, R., John, J., Sendtner, M., Wittinghofer, A.   +5 more
core   +2 more sources

Expression and Function of Neurotrophins and Their Receptors in Cultured Human Keratinocytes [PDF]

, 2003
Whereas nerve growth factor has been extensively studied in human keratinocytes, little is known on the role of other members of the neurotrophin family.
Bonté, F., Dumas, M., Failla, C.M., Fila, C., Franchi, J., Marconi, A., Maurelli, R., Pincelli, C., Romagnoli, G., Terracina, M.   +9 more
core   +1 more source

Nerve growth factor binding domain of the nerve growth factor receptor. [PDF]

Proceedings of the National Academy of Sciences, 1991
A structural analysis of the rat low-affinity nerve growth factor (NGF) receptor was undertaken to define the NGF binding domain. Mutant NGF receptor DNA constructs were expressed in mouse fibroblasts or COS cells, and the ability of the mutant receptor to bind NGF was assayed.
Catherine M. Bitler, Eric M. Shooter, Monte J. Radeke, Andrew A. Welcher   +3 more
openaire   +3 more sources

Dynamics of expression rates of growth factor proteins in psoriatic patients receiving a phototherapy

Vestnik Dermatologii i Venerologii, 2017
Goal. To study the dynamics of expression rates of growth factor proteins in psoriatic patients receiving the PUVA therapy. Materials and methods. The authors conducted a study of 30 patients with psoriasis vulgaris treated with the PUVA therapy.
V. V. Chikin, M. B. Zhilova, V. A. Smolyannikova, M. A. Nefedova   +3 more
doaj   +1 more source

Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury

Neural Regeneration Research, 2022
The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited, especially in case of severe injury. This often leads to poor motor function and permanent disability.
Kamilla Faritovna Idrisova, Alina Kazymovna Zeinalova, Galina Andreevna Masgutova, Alexey Andreevich Bogov, Cinzia Allegrucci, Valeriia Yurievna Syromiatnikova, Ilnur Ildusovich Salafutdinov, Ekaterna Evgenievna Garanina, Dina Ivanovna Andreeva, Adilet Abdullaatovich Kadyrov, Albert Anatolevich Rizvanov, Ruslan Faridovich Masgutov   +11 more
doaj   +1 more source

Anti-nerve growth factor in pain management: current evidence

Journal of Pain Research, 2016
There continues to be an unmet need for safe and effective pain medications. Opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) dominate the clinical landscape despite limited effectiveness and considerable side-effect profiles.
David S Chang, E. Hsu, D. Hottinger, Steven P. Cohen   +3 more
semanticscholar   +1 more source

17β-Estradiol Enhances the Production of Nerve Growth Factor in THP-1-Derived Macrophages or Peripheral Blood Monocyte-Derived Macrophages [PDF]

, 2003
We examined in vitro effects of 17β-estradiol (E2) on nerve growth factor production by macrophages derived from monocytic cell line THP-1-or periphereal blood monocytes.
Kanda, Naoko, Watanabe, Shinichi
core   +1 more source

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

Neural Regeneration Research, 2020
Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro, Alessia Giovannelli, Angelica Foggetti, Luisa Muratori, Stefano Geuna, Giorgia Novajra, Isabelle Perroteau   +6 more
doaj   +1 more source

CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation

Frontiers in Molecular Neuroscience, 2021
Nerve growth factor (NGF) stimulates numerous cellular physiological processes, including growth, differentiation, and survival, and maintains the phenotype of several neuronal types.
Luciana Sampieri, Luciana Sampieri, Macarena Funes Chabán, Macarena Funes Chabán, Pablo Di Giusto, Pablo Di Giusto, Victoria Rozés-Salvador, Cecilia Alvarez, Cecilia Alvarez   +8 more
doaj   +1 more source

Mechanisms of nerve growth factor signaling in bone nociceptors and in an animal model of inflammatory bone pain

Molecular Pain, 2017
Sequestration of nerve growth factor has been used successfully in the management of pain in animal models of bone disease and in human osteoarthritis.
S. Nencini, M. Ringuet, Dong-Hyun Kim, Yu-Jen Chen, C. Greenhill, J. Ivanusic   +5 more
semanticscholar   +1 more source