ATP Released by Injured Neurons Activates Schwann Cells [PDF]
, 2016 Injured nerve terminals of neuromuscular junctions (NMJs) can regenerate. This remarkable and complex response is governed by molecular signals that are exchanged among the cellular components of this synapse: motor axon nerve terminal (MAT ...
Cesare eMontecucco +8 more
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Primary Bone Marrow Mesenchymal Stromal Cells Rescue the Axonal Phenotype of Twitcher Mice
Cell Transplantation, 2014 Krabbe's disease (KD) is a demyelinating disorder caused by the deficiency of lysosomal galactocerebrosi-dase (GALC), affecting both the central (CNS) and the peripheral nervous system (PNS).
Catarina Oliveira Miranda +7 more
doaj +1 more source
Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts [PDF]
, 2016 Acellular nerve allografts (ANAs) and other nerve constructs do not reliably facilitate axonal regeneration across long defects (>3 cm). Causes for this deficiency are poorly understood.
Ee, Xueping +11 more
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Structural and molecular characteristics of axons in the long head of the biceps tendon [PDF]
, 2020 The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain.
Blumer, Roland +7 more
core +1 more source
Advances and Pitfalls of Cell Therapy in Metabolic Leukodystrophies
Cell Transplantation, 2013 Leukodystrophies are a group of disorders characterized by myelin dysfunction, either at the level of myelin formation or maintenance, that affect the central nervous system (CNS) and also in some cases, to a lesser extent, the peripheral nervous system (
Catarina Oliveira Miranda +3 more
doaj +1 more source
The role of vascularization in nerve regeneration of nerve graft
Neural Regeneration Research, 2020 Vascularization is an important factor in nerve graft survival and function. The specific molecular regulations and patterns of angiogenesis following peripheral nerve injury are in a broad complex of pathways.
T. Saffari +4 more
semanticscholar +1 more source
Neurotrophic factors and corneal nerve regeneration [PDF]
, 2017 The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
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Nano-Engineered Environment for Nerve Regeneration: Scaffolds, Functional Molecules and Stem Cells [PDF]
, 2016 One of the most complex systems in the human body is the nervous system, which is divided into the central and peripheral nervous systems. The regeneration of the CNS is a complex and challenging biological phenomenon hindered by the low regenerative ...
He, L +7 more
core +6 more sources
Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment
Cells, 2020 By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
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The Role of Spastin in Axon Biology
Frontiers in Cell and Developmental Biology, 2022 Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body
Ana Catarina Costa +2 more
doaj +1 more source