Results 71 to 80 of about 1,942,100 (397)
Treatment of peroneal nerve injuries with simultaneous tendon transfer and nerve exploration [PDF]
, 2014 Background Common peroneal nerve palsy leading to foot drop is difficult to manage and has historically been treated with extended bracing with expectant waiting for return of nerve function.
Cederna, Paul +8 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Considerations in Nerve Repair [PDF]
Baylor University Medical Center Proceedings, 2003 (2003). Considerations in Nerve Repair. Baylor University Medical Center Proceedings: Vol. 16, No. 2, pp. 152-156.
Larry M, Wolford, Eber L L, Stevao
openaire +2 more sources
Medical implantable devices for the controlled release of anti-TGF-beta1 in the repair of peripheral nerve injuries [PDF]
, 2004 The development of novel bioartificial nerve grafts which release soluble therapeutic agents, shows great promises guiding the extension of the injured axons and optimizing and improving the degree and specificity of neural outgrowth.
Brown, R.A. +4 more
core
Bioactive Silk‐Based Nerve Guidance Conduits for Augmenting Peripheral Nerve Repair
Advanced Healthcare Materials, 2018 Repair of peripheral nerve injuries depends upon complex biology stemming from the manifold and challenging injury‐healing processes of the peripheral nervous system.
Adrián Magaz +5 more
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Pathological Grade-Associated Transcriptome Profiling of lncRNAs and mRNAs in Gliomas
Frontiers in Oncology, 2020 The aim of the present study was to explore the expression profiles of lncRNAs and mRNAs in glioma patients and to elucidate any potential relationship between lncRNAs and mRNAs in glioma.
Junlong Sun +23 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related
Wenjing Ma +9 more
doaj +1 more source
Engineering peripheral nerve repair [PDF]
Current Opinion in Biotechnology, 2013 Current approaches for treating peripheral nerve injury have resulted in promising, yet insufficient functional recovery compared to the clinical standard of care, autologous nerve grafts. In order to design a construct that can match the regenerative potential of the autograft, all facets of nerve tissue must be incorporated in a combinatorial therapy.
Laura M, Marquardt +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source