Results 221 to 230 of about 982,945 (306)

Single-Tube Nested PCR Using Immobilized Internal Primers

open access: yesBioTechniques, 2002
F.G.C. Abath   +5 more
doaj   +1 more source

From glacial echoes to timber pathways: Climatic–historical drivers and timber‐trade influence on the phylogeography of Ips sexdentatus in the Basque Country

open access: yesAgricultural and Forest Entomology, EarlyView.
Ips sexdentatus is expanding across southern Europe, attacking multiple Pinus species and showing the ability to colonize trees at early stages of decline. Genetic analysis of 668 individuals revealed 106 haplotypes, with Iberian populations as diversity hotspots, reflecting long‐term refugial persistence alongside more recent demographic expansion ...
Dimitrios N. Avtzis   +4 more
wiley   +1 more source

Evaluation of Two Multiplexed qPCR Assays for Malaria Detection and Speciation: A Comparative Study With Nested PCR and Microscopy. [PDF]

open access: yesJ Parasitol Res
Muyidi AA   +11 more
europepmc   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

open access: yesBrain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma   +12 more
wiley   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu   +14 more
wiley   +1 more source

MEN1 Deficiency Drives Lung Cancer Progression via Activation of MMP10‐Mediated Angiogenesis

open access: yesCancer Science, EarlyView.
MEN1 deficiency promotes JunD‐mediated upregulation of MMP10 expression, which cleaves pro‐HB‐EGF and activates endothelial EGFR. This triggers the PI3K/Akt and MEK/ERK signaling pathways, thereby driving angiogenesis and tumor progression. MMP10 inhibitor treatment blocks this cleavage, suppresses EGFR signaling, and thereby delays malignant ...
Chengyu Wei   +17 more
wiley   +1 more source

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