Results 231 to 240 of about 982,945 (306)

Targeting the NR3C1‐ACSL4 Axis Triggers Ferroptosis to Overcome Radioresistance in Prostate Cancer

open access: yesCancer Science, EarlyView.
The glucocorticoid receptor NR3C1 drives prostate cancer radioresistance by upregulating ACSL4. High ACSL4 levels create a lipid metabolic vulnerability. The clinical agent DHA synergizes with ACSL4 to induce lipid peroxidation and ferroptosis, effectively overcoming radioresistance.
Jing Yang   +7 more
wiley   +1 more source

Assessing the Sensitivity of Nested PCR Followed by Direct Sequencing on Exosomal DNA for EGFR Mutation Detection in NSCL [PDF]

open access: yesIran Biomed J
Jahani MM   +10 more
europepmc   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

open access: yesCancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren   +11 more
wiley   +1 more source

Phylogenomic analysis of ultraconserved elements clarifies relationships and morphological evolution in Cryptoplacoidea (Mollusca: Polyplacophora)

open access: yesCladistics, EarlyView.
Abstract Targeted enrichment of ultraconserved elements (UCEs) is a powerful tool for resolving phylogeny in groups with limited morphological or molecular data. Here, we use UCEs to reconstruct the first comprehensive phylogeny of the chiton superfamily Cryptoplacoidea, including museum material up to 133 years old.
Katarzyna Vončina   +4 more
wiley   +1 more source

Evolutionary framework and tribal circumscription of Amaranthaceae sensu stricto based on a comprehensive phylogenomic analysis

open access: yesCladistics, EarlyView.
Abstract The evolutionary history of Amaranthaceae sensu stricto (s.s.) has been shaped by multiple whole‐genome duplications and rapid radiations, producing an ecologically diverse lineage whose internal relationships have long remained unresolved.
Tina Kiedaisch   +3 more
wiley   +1 more source

A revised classification system of the marronoid clade of spiders (Araneae), based on dense sampling phylogenomics and comparative morphology

open access: yesCladistics, EarlyView.
Abstract The marronoid clade is a globally distributed, ecologically diverse group of spiders. It is an important faunal component in both natural and synanthropic environments, and even found in aquatic and extreme habitats such as desert salt flats. The systematics of the marronoid clade has been notoriously unstable due to the widespread character ...
Jonas O. Wolff   +10 more
wiley   +1 more source

Exploring mosquito abundance and Plasmodium infection through nested-PCR: implications for disease surveillance and control. [PDF]

open access: yesSci Rep
Abbas H   +12 more
europepmc   +1 more source

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