Targeting the NR3C1‐ACSL4 Axis Triggers Ferroptosis to Overcome Radioresistance in Prostate Cancer
The glucocorticoid receptor NR3C1 drives prostate cancer radioresistance by upregulating ACSL4. High ACSL4 levels create a lipid metabolic vulnerability. The clinical agent DHA synergizes with ACSL4 to induce lipid peroxidation and ferroptosis, effectively overcoming radioresistance.
Jing Yang +7 more
wiley +1 more source
Assessing the Sensitivity of Nested PCR Followed by Direct Sequencing on Exosomal DNA for EGFR Mutation Detection in NSCL [PDF]
Jahani MM +10 more
europepmc +1 more source
Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren +11 more
wiley +1 more source
Corrigendum to "Primary and Nested PCR Amplification of B1 Gene to Confirm Seropositivity of Toxoplasmosis Among Cancer Patients in Sri Lanka". [PDF]
europepmc +1 more source
Abstract Targeted enrichment of ultraconserved elements (UCEs) is a powerful tool for resolving phylogeny in groups with limited morphological or molecular data. Here, we use UCEs to reconstruct the first comprehensive phylogeny of the chiton superfamily Cryptoplacoidea, including museum material up to 133 years old.
Katarzyna Vončina +4 more
wiley +1 more source
Development and Evaluation of a Semi-Nested PCR Method Based on the 18S ribosomal RNA Gene for the Detection of Babesia aktasi Infections in Goats. [PDF]
Ulucesme MC, Ozubek S, Aktas M.
europepmc +1 more source
Abstract The evolutionary history of Amaranthaceae sensu stricto (s.s.) has been shaped by multiple whole‐genome duplications and rapid radiations, producing an ecologically diverse lineage whose internal relationships have long remained unresolved.
Tina Kiedaisch +3 more
wiley +1 more source
Abstract The marronoid clade is a globally distributed, ecologically diverse group of spiders. It is an important faunal component in both natural and synanthropic environments, and even found in aquatic and extreme habitats such as desert salt flats. The systematics of the marronoid clade has been notoriously unstable due to the widespread character ...
Jonas O. Wolff +10 more
wiley +1 more source
Correction to: UPrimer: A Clade-Specific Primer Design Program Based on Nested-PCR Strategy and Its Applications in Amplicon Capture Phylogenomics. [PDF]
europepmc +1 more source
Exploring mosquito abundance and Plasmodium infection through nested-PCR: implications for disease surveillance and control. [PDF]
Abbas H +12 more
europepmc +1 more source

