Vital NETosis vs. suicidal NETosis during normal pregnancy and preeclampsia
Frontiers in Cell and Developmental Biology, 2023 Background: NETosis occurs in the context of infection or inflammation and results in the expulsion of decondensed DNA filaments called NETs (Neutrophil Extracellular Traps) into the extracellular environment.
Florence Guillotin +19 more
exaly +5 more sources
In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review. [PDF]
PLoS ONE, 2017 BackgroundMultiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation (NETosis) have been described. Since there is much variation in study design and results, our aim was to create a systematic review of NETosis inducers and perform a ...
Tamara Hoppenbrouwers +10 more
doaj +2 more sources
Molecular mechanisms and therapeutic target of NETosis in diseases
MedComm, 2022 Evidence shows that neutrophils can protect the host against pathogens in multiple ways, including the formation and release of neutrophil extracellular traps (NETs).
weiqi Hong
exaly +2 more sources
Simplified flow cytometric quantification of human neutrophil extracellular traps (NETs) [PDF]
Journal of InflammationSeveral cellular pathways lead to the formation of neutrophil extracellular traps (NETs), a form of cell death (NETosis), distinct from apoptotic and necrotic cell death.
G. Rinaldi +10 more
doaj +2 more sources
Phytochemicals as potential inhibitors of NETosis: implications for immunothrombosis and chronic disease management [PDF]
BMC Complementary Medicine and TherapiesBackground NETosis, a specialized form of neutrophil cell death, plays a dual role in immune regulation. While NET formation is essential for capturing pathogens, excessive NETosis contributes to immunothrombosis, oxidative stress, and tissue damage ...
Chen Juanlu +3 more
doaj +2 more sources
A semi-automated imaging and analysis pipeline for NET quantification and temporal-profiling of NETosis [PDF]
Frontiers in ImmunologyNETosis is a distinct form of neutrophil cell death involved in innate immunity and characterized by the release of DNA, that when dysregulated contributes to tissue damage and target-organ injury.
Chloé Landry +8 more
doaj +2 more sources
Skin and Systemic Inflammation in Schnitzler's Syndrome Are Associated With Neutrophil Extracellular Trap Formation [PDF]
Frontiers in Immunology, 2019 Schnitzler's syndrome is a rare autoinflammatory disorder characterized by interleukin-1ß-mediated and neutrophil-dominated inflammation. Neutrophil extracellular traps (NETs) are web-like structures of decondensed chromatin, histones, and antimicrobial ...
Hanna Bonnekoh +9 more
doaj +5 more sources
ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging [PDF]
Advanced ScienceNeutrophil NETosis is markedly dysregulated in the aging body. Bone marrow serves as the powerhouse of neutrophil differentiation, while the state of neutrophil NETosis therein and its relationship with bone aging remains largely elusive.
Yutong Guo +6 more
doaj +2 more sources
Redox BiologyPrimary graft dysfunction (PGD) is a severe form of acute lung injury resulting from lung ischemia/reperfusion injury (I/R) in lung transplantation (LTx), associated with elevated post-transplant morbidity and mortality rates.
Zongmei Wen
exaly +3 more sources
Netosis in the pathogenesis of antiphospholipid syndrome and systemic lupus erythematosus
Современная ревматология, 2021 Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases. In recent years, APS has been considered as an autoimmune thrombo-inflammatory disease.
K. S. Nurbaeva +2 more
doaj +1 more source