Results 21 to 30 of about 18,973 (244)
Earthworm coelomocyte extracellular traps : structural and functional similarities with neutrophil NETs [PDF]
, 2018 ROD UJ /
Joanna Homa
core +2 more sources
Effect of Adhesion and Substrate Elasticity on Neutrophil Extracellular Trap Formation
Frontiers in Immunology, 2019 Neutrophils are the most abundant type of white blood cells. Upon stimulation, they are able to decondense and release their chromatin as neutrophil extracellular traps (NETs). This process (NETosis) is part of immune defense mechanisms but also plays an
Luise Erpenbeck +12 more
doaj +1 more source
Mycobacterium tuberculosis Drives Expansion of Low-Density Neutrophils Equipped With Regulatory Activities [PDF]
, 2019 In human tuberculosis (TB) neutrophils represent the most commonly infected phagocyte but their role in protection and pathology is highly contradictory.
La Manna, M. P. +8 more
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Journal of Biomedical Science, 2020 Background Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of innate immunity and of Th1 immune responses ...
Patricia Ruiz-Limon +14 more
doaj +1 more source
SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities [PDF]
, 2019 Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the ...
Botti L. +12 more
core +3 more sources
Oncoscience, 2015 A large proportion of cancer-related deaths are caused by thrombosis and general organ failure. Although the awareness of tumor-induced systemic effects has increased significantly in recent years, current knowledge is still mainly restricted to metastatic sites.
Jessica, Cedervall, Anna-Karin, Olsson
openaire +2 more sources
Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]
, 2019 Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio +5 more
core +1 more source
Diverse Roles of NETosis in the Pathogenesis of Lupus
Frontiers in Immunology, 2022 NETosis is a form of neutrophil cell death during which extracellular fibrillary structures composed of cytosolic and granule proteins assembled on scaffolds of decondensed chromatin, called neutrophil extracellular traps (NETs), are released.
Meiying Wang +8 more
doaj +1 more source
Platelets: New bricks in the building of neutrophil extracellular traps [PDF]
, 2016 In addition to being key elements in hemostasis and thrombosis, platelets have an important role in the inflammatory and innate immune response. This activity is associated with their capability to recognize pathogens through the expression of toll-like ...
Carestia, Agostina +2 more
core +1 more source
ROS induces NETosis by oxidizing DNA and initiating DNA repair
Cell Death Discovery, 2021 Reactive oxygen species (ROS) are essential for neutrophil extracellular trap (NET) formation or NETosis. Nevertheless, how ROS induces NETosis is unknown. Neutrophil activation induces excess ROS production and a meaningless genome-wide transcription to
Dhia Azzouz +2 more
doaj +1 more source