Results 41 to 50 of about 18,973 (244)

Furanoid F-Acid F6 Uniquely Induces NETosis Compared to C16 and C18 Fatty Acids in Human Neutrophils

Biomolecules, 2018
Various biomolecules induce neutrophil extracellular trap (NET) formation or NETosis. However, the effect of fatty acids on NETosis has not been clearly established. In this study, we focused on the NETosis-inducing ability of several lipid molecules. We
Meraj A. Khan, Cecil Pace-Asciak, Jassim M. Al-Hassan, Mohammad Afzal, Yuan Fang Liu, Sosamma Oommen, Bincy M. Paul, Divya Nair, Nades Palaniyar   +8 more
doaj   +1 more source

Neutrophil extracellular traps (NETs) : formation and implications [PDF]

, 2013
Neutrophils are cells of the immune system which freely circulate in blood vessels and are recruited to the inflammation sites when the human organism responds to microbial infections.
Rąpała-Kozik, Maria, Zawrotniak, Marcin   +1 more
core   +1 more source

neutrophils are on the payroll [PDF]

, 2015
Viral hemorrhagic fever caused by hantaviruses is an emerging infectious disease for which suitable treatments are not available. In order to improve this situation a better understanding of hantaviral pathogenesis is urgently required.
Krüger, Detlev H., Raftery, Martin J., Schönrich, Günther   +2 more
core   +1 more source

Functional Verification and Prognostic Value of Neutrophil Extracellular Trap-Related Genes in Pancreatic Cancer Progression

Frontiers in Bioscience-Landmark
Background: Pancreatic carcinoma (PC), a severely malignant neoplasm of the digestive system, is characterized by an unfavorable prognosis.
Jiaxin Xu, Liying Tu, Lijing Ma, Qisheng Tang, Yu Cao, Lihong Jiang   +5 more
doaj   +1 more source

2-Chlorofatty acids: lipid mediators of neutrophil extracellular trap formation

Journal of Lipid Research, 2018
Neutrophils form neutrophil extracellular traps (NETs), which have been implicated in microcirculatory plugging. NET formation (NETosis) involves the fusion of granule and nuclear contents, which are then released in the extracellular space ...
ElisaN.D. Palladino, Lalage A. Katunga, Grant R. Kolar, David A. Ford   +3 more
doaj   +1 more source

Increased levels of NETosis biomarkers in high-grade serous ovarian cancer patients’ biofluids: Potential role in disease diagnosis and management

Frontiers in Immunology, 2023
IntroductionHigh-grade serous ovarian cancer (HGSOC) is the second most frequent gynecological malignancy but the most lethal, partially due to the spread of the disease through the peritoneal cavity. Recent evidence has shown that, apart from their role
Sarai Tomás-Pérez, Julia Oto, Cristina Aghababyan, Cristina Aghababyan, Raquel Herranz, Aitor Cuadros-Lozano, Aitor Cuadros-Lozano, Eva González-Cantó, Bárbara Mc Cormack, Judith Arrés, María Castaño, Fernando Cana, Laura Martínez-Fernández, Laura Martínez-Fernández, Núria Santonja, Rocío Ramírez, Alejandro Herreros-Pomares, Alejandro Herreros-Pomares, Sarai Cañete-Mota, Antoni Llueca, Antoni Llueca, Antoni Llueca, Josep Marí-Alexandre, Josep Marí-Alexandre, Pilar Medina, Juan Gilabert-Estellés, Juan Gilabert-Estellés, Juan Gilabert-Estellés   +27 more
doaj   +1 more source

Peptidylarginine deiminases as drug targets in neonatal hypoxic-ischemic encephalopathy [PDF]

, 2016
Oxygen deprivation and infection are major causes of perinatal brain injury leading to cerebral palsy and other neurological disabilities. The identification of novel key factors mediating white and grey matter damage are crucial to allow better ...
Adhami, Alonso-Alconada, Azad, Baburamani, Balandraud, Balduini, Block, Bozdag, Brinkmann, Brown, Byrd, Chavanas, Chavanas, Cherian, Cherrington, Choi, Christophorou, Cotten, Cui, Culman, David, Dingley, Dixon, Douglas-Escobar, Dragunow, Dwivedi, Erny, Fan, Faulkner, Ferretti, Ferriero, Fox, Fricker, Garcia-Romo, Ginet, Goyal, Guerrin, Gupta, Gupta, György, Hagberg, Hagberg, Hagiwara, Horibata, Imm, Ireland, Ireland, Karlsson, Kearney, Keilhoff, Kendall, Kendall, Kessenbrock, Keunen, Kholia, Knuckley, Kopatz, Kumral, Kurinczuk, Lande, Lange, Lange, Latuga, Law, Lee, Li, Li, Li, Loos, Loos, Luo, Ma, Mallard, Mallard, Marcos, Mari, Martin, Mastronardi, McCormack, Mirza, Moelants, Moelants, Musse, Neeli, Neeli, Neher, Neher, Neniskyte, Neumann, Northington, Perlman, Pirianov, Prempunpong, Proost, Robertson, Robertson, Rocha-Ferreira, Romano-Keeler, Romero, Sharda, Sherman, Simak, Slack, Spengler, Stenberg, Stys, Subramanian, Trabocchi, U, Uria-Avellanal, Villanueva, Vossenaar, Wang, Wang, Wassink, Wei, Witalison, Wood, Wright, Wu, Wu, Wyatt, Wyatt, Yektaei-Karin, Yi, Yost, Zhu, Zhu, Zhu, Zhu, Zipfel   +130 more
core   +2 more sources

NETosis occurs independently of neutrophil serine proteases [PDF]

Journal of Biological Chemistry, 2020
Neutrophils are primary host innate immune cells defending against pathogens. One proposed mechanism by which neutrophils prevent the spread of pathogens is NETosis, the extrusion of cellular DNA resulting in neutrophil extracellular traps (NETs). The protease neutrophil elastase (NE) has been implicated in the formation of NETs through proteolysis of ...
Paulina Kasperkiewicz, Anne Hempel, Tomasz Janiszewski, Sonia Kołt, Scott J. Snipas, Marcin Drag, Guy S. Salvesen   +6 more
openaire   +2 more sources

Investigating neutrophil cell death in TB pathogenesis [version 1; peer review: 2 approved]

Gates Open Research, 2021
Background: Neutrophils are one of the major early role players in antimycobacterial immunity. Upon infection, neutrophils can undergo NETosis, a cell death characterized by release of neutrophil extracellular traps (NETs).
Thabo Mpotje, Kerishka Rajkumar-Bhugeloo, Thumbi Ndung'u, Duran Ramsuran, Mohlopheni J Marakalala, Denelle Moodley, Kimone L Fisher   +6 more
doaj   +1 more source

Neutrophil extracellular traps as innate immune reaction against the emerging apicomplexan parasite Besnoitia besnoiti [PDF]

, 2014
Besnoitia besnoiti infection in cattle is an important emerging protozoan disease in Europe causing economic losses and severe clinical signs, such as generalized dermatitis, orchitis, and vulvitis in affected animals. Neutrophil extracellular trap (NET)
Cortes, Helder, Hermosilla, Carlos, Muñoz Caro, Tamara, Silva, Liliana M. R., Taubert, Anja   +4 more
core   +2 more sources