Results 41 to 50 of about 1,925,336 (327)
Frontiers in Cell and Developmental Biology, 2023 Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma +13 more
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Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration
eLife, 2020 During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we ...
Shashank Gandhi +5 more
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Evolution of the New Head by gradual acquisition of neural crest regulatory circuits
Nature, 2019 The neural crest, an embryonic stem-cell population, is a vertebrate innovation that has been proposed to be a key component of the ‘new head’, which imbued vertebrates with predatory behaviour1,2.
Megan L. Martik +6 more
semanticscholar +1 more source
Cell Reports, 2023 Summary: Neural crest cells are multipotent cells that delaminate from the neuroepithelium, migrating throughout the embryo. Aberrant migration causes developmental defects.
Lisa Dobson +6 more
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Genome Research, 2019 Cell fate commitment involves the progressive restriction of developmental potential. Recent studies have shown that this process requires not only shifts in gene expression but also an extensive remodeling of the epigenomic landscape.
Megan Rothstein, M. Simoes-Costa
semanticscholar +1 more source
Adipose stromal cells contain phenotypically distinct adipogenic progenitors derived from neural crest. [PDF]
PLoS ONE, 2013 Recent studies have shown that adipose-derived stromal/stem cells (ASCs) contain phenotypically and functionally heterogeneous subpopulations of cells, but their developmental origin and their relative differentiation potential remain elusive.
Yoshihiro Sowa +6 more
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Specification and formation of the neural crest: Perspectives on lineage segregation
Genesis, 2019 The neural crest is a fascinating embryonic population unique to vertebrates that is endowed with remarkable differentiation capacity. Thought to originate from ectodermal tissue, neural crest cells generate neurons and glia of the peripheral nervous ...
Maneeshi S. Prasad +2 more
semanticscholar +1 more source
Neural Crest Specification by Inhibition of the ROCK/Myosin II Pathway
Stem Cells, 2014 Kyeongmi Kim +2 more
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Cranial Neural Crest Transplants [PDF]
Cold Spring Harbor Protocols, 2018 The transplantation of cranial neural crest (CNC) expressing green fluorescent protein (GFP) in Xenopus laevis has allowed researchers not only to assess CNC migration in vivo but also to address many other experimental questions. Coupled with loss- or gain-of-function experiments, this technique can be used to characterize the function of specific ...
openaire +2 more sources
Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells
Science, 2015 Elsy Buitrago-Delgado +4 more
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