Results 51 to 60 of about 112,561 (244)
Advanced Functional Materials, EarlyView.Herein, a comprehensive framework that enabled the optimization of colloidal solubility within a high‐dimensional parameter space and study of reversible assembly processes is developed. This data‐driven workflow integrated innovations including the robotic platform for automated AuNPs functionalization, machine learning for predicting and revealing ...
Yueyang Gao +5 more
wiley +1 more source
Development and evolution of the neural crest: An overview [PDF]
, 2012 The neural crest is a multipotent and migratory cell type that forms transiently in the developing vertebrate embryo. These cells emerge from the central nervous system, migrate extensively and give rise to diverse cell lineages including melanocytes ...
Bronner, Marianne E. +1 more
core +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source
Case of a 16‐Year‐Old Boy With Headache, Vomiting, and Behavioral Changes
Annals of Clinical and Translational Neurology, EarlyView.
Kundian Guo, Zhen Hong
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie +5 more
wiley +1 more source
Dorsal hindbrain ablation results in rerouting of neural crest migration and changes in gene expression, but normal hyoid development [PDF]
, 1997 Our previous studies have shown that hindbrain neural tube cells can regulate to form neural crest cells for a limited time after neural fold removal (Scherson, T., Serbedzija, G., Fraser, S. E. and Bronner-Fraser, M. (1993).
Bronner-Fraser, Marianne +4 more
core
Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer +10 more
wiley +1 more source