Results 51 to 60 of about 4,193,744 (287)

The role of axon guidance molecules in the pathogenesis of epilepsy

open access: yesNeural Regeneration Research
Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms
Zheng Liu, Chunhua Pan, Hao Huang
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Neural and hormonal mechanisms of appetite regulation during eating

open access: yesFrontiers in Nutrition
Numerous animal and clinical studies have demonstrated that the arcuate nucleus of the hypothalamus, a central regulator of appetite, plays a significant role in modulating feeding behavior.
Xurui Sun   +5 more
doaj   +1 more source

Neural Conduction Along Postretinal Visual Pathways in Glaucoma

open access: yesFrontiers in Aging Neuroscience, 2021
Purpose: This study was conducted in order to evaluate retinal ganglion cell (RCG) function and the neural conduction along the postretinal large and small axons and its correlation with retinal nerve fiber layer thickness (RNFL-T) in open-angle glaucoma
Vincenzo Parisi   +7 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Genetic Signatures of Competitive Performance in Burmese Gamecocks: A Transcriptomic Analysis

open access: yesBiology
Understanding the genetic basis of high-performance animals is vital for biological insight and breeding. This study aimed to identify genetic factors distinguishing champion gamecocks (Gallus gallus domesticus) from less successful ones, representing ...
Supawadee Piratae   +4 more
doaj   +1 more source

SnapShot: Neural Pathways that Control Feeding

open access: yesCell Metabolism, 2014
This SnapShot provides an overview of brain systems such as the hypothalamus and brainstem that sense and integrate nutritional signals controlling eating.
Myers, Martin G., Olson, David P.
openaire   +2 more sources

Functional Neural–Bone Marrow Pathways [PDF]

open access: yesHypertension, 2014
Treatment-resistant hypertension (TRHT) is characterized by persistently high arterial blood pressure (BP), partly as a result of a dysfunctional autonomic nervous system (ANS), wherein sympathetic drive/norepinephrine spillover is increased and parasympathetic drive is decreased.1–3 The difficulty in treatment of TRHT arises precisely from this partly
Jasenka Zubcevic   +7 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Neural pathways in nutrient sensing and insulin signaling

open access: yesFrontiers in Physiology, 2022
Nutrient sensing and metabolic homeostasis play an important role in the proper growth and development of an organism, and also in the energy intensive process of reproduction.
Anuradha Ratnaparkhi   +2 more
doaj   +1 more source

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