Results 71 to 80 of about 395,346 (230)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Individuals’ preference on reading pathways influences the involvement of neural pathways in phonological learning

open access: yesFrontiers in Psychology, 2022
IntroductionExisting behavioral and neuroimaging studies revealed inter-individual variability in the selection of the two phonological routes in word reading.
Jie Dong   +16 more
doaj   +1 more source

A vital dye analysis of the timing and pathways of avian trunk neural crest cell migration [PDF]

open access: yes, 1989
To permit a more detailed analysis of neural crest cell migratory pathways in the chick embryo, neural crest cells were labelled with a nondeleterious membrane intercalating vital dye, DiI.
Bronner-Fraser, Marianne E.   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Interlimb neural interactions in the corticospinal pathways

open access: yesJournal of Physical Fitness and Sports Medicine, 2014
Corticospinal excitability is known to be modulated during voluntary muscle contraction of distal limbs. Although a large number of studies have demonstrated the variety of modulations in corticospinal excitability during distal limb movement, those ...
Toshiki Tazoe, Tomoyoshi Komiyama
doaj   +1 more source

Neurorhetoric, Race, and the Law: Toxic Neural Pathways and Healing Alternatives [PDF]

open access: yes, 2017
Neurorhetoric is the study of how rhetoric shapes the human brain. At the forefront of science and communication studies, neurorhetoric challenges many preconceptions about how humans respond to persuasive stimuli.
Jewel, Lucy
core   +1 more source

The Contribution of Thalamocortical Core and Matrix Pathways to Sleep Spindles. [PDF]

open access: yes, 2016
Sleep spindles arise from the interaction of thalamic and cortical neurons. Neurons in the thalamic reticular nucleus (TRN) inhibit thalamocortical neurons, which in turn excite the TRN and cortical neurons.
Cash, Sydney S   +2 more
core   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Neural Networks, Cell Genome and Interactome Nonlinear Dynamic Models [PDF]

open access: yes, 2011
Operational logic and bioinformatics models of nonlinear dynamics in complex functional systems such as neural networks, genomes and cell interactomes are proposed.
I. C. Baianu
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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