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The utility of stem cells for neural regeneration [PDF]
Brain and Neuroscience Advances, 2018 The use of stem cells in biomedical research is an extremely active area of science. This is because they provide tools that can be used both in vivo and vitro to either replace cells lost in degenerative processes, or to model such diseases to elucidate their underlying mechanisms.
Kirsty Goncalves, Stefan Przyborski
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Cardiac Neural Crest and Cardiac Regeneration
Cells, 2022 Neural crest cells (NCCs) are a vertebrate-specific, multipotent stem cell population that have the ability to migrate and differentiate into various cell populations throughout the embryo during embryogenesis. The heart is a muscular and complex organ whose primary function is to pump blood and nutrients throughout the body.
Shannon Erhardt, Jun Wang
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Goal-Directed Planning for Habituated Agents by Active Inference Using a Variational Recurrent Neural Network [PDF]
, 2020 It is crucial to ask how agents can achieve goals by generating action plans using only partial models of the world acquired through habituated sensory-motor experiences.
Matsumoto, Takazumi, Tani, Jun
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Neural Stem Cells: Promoting Axonal Regeneration and Spinal Cord Connectivity
Cells, 2021 Spinal cord injury (SCI) leads to irreversible functional impairment caused by neuronal loss and the disruption of neuronal connections across the injury site.
Camila Marques de Freria +3 more
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Pure-silk fibroin hydrogel with stable aligned micropattern toward peripheral nerve regeneration
Nanotechnology Reviews, 2021 Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is a key to accelerate nerve regeneration.
Gu Xinyi +6 more
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Biomolecules, 2023 The dysfunction of astrocytes in response to environmental factors contributes to many neurological diseases by impacting neuroinflammation responses, glutamate and ion homeostasis, and cholesterol and sphingolipid metabolism, which calls for ...
Zhenwei Qian +4 more
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Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations [PDF]
, 2001 Multipotent stem cells are clonal cells that self-renew as well as differentiate to regenerate adult tissues. Whereas stem cells and their fates are known by unique genetic marker studies, the fate and function of these cells are best studied by their ...
Anderson, David J. +2 more
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Stem Cell Research & Therapy, 2019 s Background Spinal cord injury (SCI) is a complex and severe neurological condition. Mesenchymal stem cells (MSCs) and their secreted factors show promising potential for regenerative medicine.
Ya-Tzu Chen +6 more
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Rabphilin-3A undergoes phase separation to regulate GluN2A mobility and surface clustering
Nature Communications, 2023 GluN2A and GluN2B, two predominant Glu2N subunits of NMDARs in hippocampus and cortex, display distinct organization and mobility in the neuronal surface.
Lei Yang +9 more
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Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. [PDF]
, 2018 Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood.
Carolino, Krislyn I +13 more
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