Production of
BMC Biotechnology, 2009 Background Two sequential enzymes in the production of sialic acids, N-acetyl-D-glucosamine 2-epimerase (GlcNAc 2-epimerase) and N-acetyl-D-neuraminic acid aldolase (Neu5Ac aldolase), were overexpressed as double-tagged gene fusions.
Cheng Chung-Hsien +5 more
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Sialic acids, sialoconjugates and enzymes of their metabolism in fungi
Biotechnology & Biotechnological Equipment, 2021 Sialic acids (Sia) represent a set of derivatives of nine-carbon sugar neuraminic acid that occupy a terminal position in oligosaccharide chains located on the surface of cells. They are very important for several physiological and pathological processes,
Rumyana Eneva +4 more
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Many locks to one key: N-acetylneuraminic acid binding to proteins [PDF]
IUCrJSialic acids play crucial roles in cell surface glycans of both eukaryotic and prokaryotic organisms, mediating various biological processes, including cell–cell interactions, development, immune response, oncogenesis and host–pathogen interactions. This
KanagaVijayan Dhanabalan +3 more
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Synthesis of 9-O-Acetyl- and 4,9-Di-O-Acetyl Derivatives of the Methyl Ester of N-Acetyl-β-D-Neuraminic Acid Methylglycoside. Their Use as Models in Periodate Oxidation Studies [PDF]
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1975 Reaction of the methyl ester of N-acetyl-beta-D-neuraminic acid methyl glycoside with N-acetylimidazole yielded the corresponding 9-O-acetyl- and 4,9-di-O-acetyl derivatives.
Johan Haverkamp +4 more
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Dynamic Changes of Microbial Communities and Chemical Compounds During the Dry Processing of Coffea arabica [PDF]
Food Science &Nutrition, Volume 13, Issue 4, April 2025.Tatumella, Klebsiella, Gluconobacter, Brevundimonas, and Staphylococcus at the bacterial general level and Candida, Lachancea, Aschersonia, Cercospora, and Pichia at the fungi general level were the predominant microorganisms during the dry processing of Coffea arabica.
Xiaojing Shen +7 more
wiley +2 more sources
Neuraminic Acid Derivatives Newly Discovered in Humans: N-Acetyl-9-O-L-lactoylneuraminic Acid, N,9-O-Diacetylneuraminic Acid and N-Acetyl-2,3-dehydro-2-deoxyneuraminic Acid [PDF]
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1976 The free and glycosidically bound acylneuraminic acids from human serum and saliva and the free acylneuraminic acids from human urine have been characterized by thin-layer chromatography and gas-liquid chromatography/mass spectrometry.
Johan Haverkamp +6 more
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Stereoselective Synthesis of a C-Linked Neuraminic Acid Disaccharide: Potential Building Block for the Synthesis of C-Analogues of Polysialic acids [PDF]
Journal of Organic Chemistry, 2008 C-linked neuraminic acid disaccharide was synthesized in a diastereoselective manner from a sulfone donor and aldehyde acceptor, which was protected as a propargyl ether, through a samarium-mediated coupling reaction.
Jin Hwan Kim +3 more
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Synthesis of Nor-C-linked Neuraminic Acid Disaccharide: A Versatile Precursor of C-Analogs of Oligosialic Acids and Gangliosides [PDF]
Journal of Organic Chemistry, 2007 The Neu5Acalpha(2,8)Neu5Ac disaccharide is an important constituent of tumor related antigen, however, the O-linkage is catabolically unstable. Vaccination with a catabolically stable sialic acid C-glycoside analog might enhance immunogenicity.
Xuejun Yuan +2 more
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Characterization of the Acid Stability of Glycosidically Linked Neuraminic Acid [PDF]
Journal of Biological Chemistry, 2002 The glycosidic linkage of sialic acids is much more sensitive to acid hydrolysis than those of other monosaccharides in vertebrates. The commonest sialic acids in nature are neuraminic acid (Neu)-based and are typicallyN-acylated at the C5 position ...
Justin L. Sonnenburg +2 more
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Detection of N-glycolyl-neuraminic acid-containing glycolipids in human skin. [PDF]
Front Immunol, 2023 Manni M +8 more
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