Expression of sialic acids and other nonulosonic acids in Leptospira [PDF]
, 2012 BackgroundSialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and legionaminic acids.
Lewis, Amanda L +3 more
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BMC Biotechnology, 2009 Background Two sequential enzymes in the production of sialic acids, N-acetyl-D-glucosamine 2-epimerase (GlcNAc 2-epimerase) and N-acetyl-D-neuraminic acid aldolase (Neu5Ac aldolase), were overexpressed as double-tagged gene fusions.
Cheng Chung-Hsien +5 more
doaj +1 more source
Glycolyl-neuraminic Acid in Ox Brain Gangliosides [PDF]
Nature, 1965 IN this communication we report the presence of glycolyl-neuraminic acid in sialic acids from ox brain gangliosides. Our method of analysis consisted of the following six steps: (i) gangliosides were extracted from ox brain grey matter and purified according to a method which we have previously described1; (ii) gangliosides so obtained were hydrolysed ...
G, Tettamanti +3 more
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Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]
, 2014 Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce +6 more
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Beilstein Journal of Organic Chemistry, 2010 Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal
Arne Homann +4 more
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Glycosylated proteins preserved over millennia: N-glycan analysis of Tyrolean Iceman, Scythian Princess and Warrior. [PDF]
, 2014 An improved understanding of glycosylation will provide new insights into many biological processes. In the analysis of oligosaccharides from biological samples, a strict regime is typically followed to ensure sample integrity.
An, Hyun Joo +11 more
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Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]
, 2010 Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
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In vitro increased respiratory activity of selected oral bacteria may explain competitive and collaborative interactions in the oral microbiome [PDF]
, 2017 Understanding the driving forces behind the shifts in the ecological balance of the oral microbiota will become essential for the future management and treatment of periodontitis. As the use of competitive approaches for modulating bacterial outgrowth is
Boon, Nico +6 more
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The Lp_3561 and Lp_3562 enzymes support a functional divergence process in the lipase/esterase toolkit from Lactobacillus plantarum [PDF]
, 2016 Lactobacillus plantarum species is a good source of esterases since both lipolytic and esterase activities have been described for strains of this species. No fundamental biochemical difference exists among esterases and lipases since both share a common
de las Rivas, Blanca +5 more
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Sialic acid acquisition in bacteria - one substrate many transporters [PDF]
, 2016 The sialic acids are a family of 9-carbon sugar acids found predominantly on the cell-surface glycans of humans and other animals within the Deuterostomes and are also used in the biology of a wide range of bacteria that often live in association with ...
Thomas, Gavin Hugh
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