Results 41 to 50 of about 4,989,359 (237)

Symmetry Scheme for Amino Acid Codons [PDF]

open access: yesPhys.Rev.E65, 021912 (2002), 2003
Group theoretical concepts are invoked in a specific model to explain how only twenty amino acids occur in nature out of a possible sixty four. The methods we use enable us to justify the occurrence of the recently discovered twenty first amino acid selenocysteine, and also enables us to predict the possible existence of two more, as yet undiscovered ...
arxiv   +1 more source

A biotechnological tool for glycoprotein desialylation based on immobilized neuraminidase from Clostridium perfringens

open access: yesBiochemistry and Biophysics Reports, 2021
Background: Sialic acids are widely distributed in nature and have biological relevance owing to their varied structural and functional roles. Immobilized neuraminidase can selectively remove terminal N-acetyl neuraminic acid from glycoproteins without ...
Lucía Bidondo   +4 more
doaj  

Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines

open access: yesJournal of Experimental & Clinical Cancer Research, 2009
Background Carbohydrates embedded in the plasma membrane are one of the main actors involved in the communication of cells with the microenvironment. Neuraminic sialic acids are glycocalyx sugars that play important roles in the modulation of malignant ...
Alonso Daniel F   +3 more
doaj   +1 more source

Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]

open access: yesarXiv, 2023
Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv  

Learning the Hydrophilic, Hydrophobic and Aromatic Character of Amino Acids from their Interfacial Thermal Conductance in Water [PDF]

open access: yes, 2021
In this study, the thermal relaxation of the 20 naturally occurring amino-acids in water is investigated using transient non-equilibrium molecular-dynamics simulations. By modeling the thermal relaxation process, the relaxation times of the amino-acids in water occurs over a timescale covering 2-5 ps.
arxiv   +1 more source

Sialic acids in cancer biology and immunity.

open access: yesGlycobiology, 2016
During malignant transformation, glycosylation is heavily altered compared with healthy tissue due to differential expression of glycosyltransferases, glycosidases and monosaccharide transporters within the cancer microenvironment.
O. Pearce, H. Läubli
semanticscholar   +1 more source

The effects of carboxylic acids on the aqueous dispersion and electrophoretic deposition of ZrO2 [PDF]

open access: yesJournal of the European Ceramic Society, Volume 32, Issue 1, 2012, Pages 235-244, 2013
The agglomeration, electrokinetic properties and electrophoretic deposition behaviour of aqueous suspensions of ZrO2 with carboxylic acid additives were studied in comparison with conventional pH adjustment. It was found that citric acid imparted negative zeta-potential values and electrosteric stabilisation to particles in suspensions at all pH levels.
arxiv   +1 more source

Effect of Non-Surgical Periodontal Therapy on the Serum Sialic Acid Levels in Diabetic Patients with Periodontitis

open access: yesActa Medica, 2019
Sialic acid (SA), a family of acetylated derivatives of neuraminic acid, an acute phase reactant by itself. It usually occurs as a terminal component at the non-reducing end of carbohydrate chains of glycoproteins and glycolipids.
Reshma Suresh   +7 more
doaj   +1 more source

Nature's Starships. I. Observed Abundances and Relative Frequencies of Amino Acids in Meteorites [PDF]

open access: yes, 2014
The class of meteorites called carbonaceous chondrites are examples of material from the solar system which have been relatively unchanged from the time of their initial formation. These meteorites have been classified according to the temperatures and physical conditions of their parent planetesimals.
arxiv   +1 more source

Meteoritic Abundances of Fatty Acids and Potential Reaction Pathways in Planetesimals [PDF]

open access: yesIcarus, 2019, 319, 685-700, 2018
The origin of fatty acids on the prebiotic Earth is important as they likely formed the encapsulating membranes of the first protocells. Carbon-rich meteorites (i.e., carbonaceous chondrites) such as Murchison and Tagish Lake are well known to contain these molecules, and their delivery to the early planet by intense early meteorite bombardments ...
arxiv   +1 more source

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